2-Bromo-4'-iodoacetophenone
2-Bromo-4'-iodoacetophenone
CAS: 31827-94-8
Molecular Formula: C8H6BrIO
2-Bromo-4'-iodoacetophenone - Names and Identifiers
2-Bromo-4'-iodoacetophenone - Physico-chemical Properties
| Molecular Formula | C8H6BrIO |
| Molar Mass | 324.94 |
| Density | 2.080±0.06 g/cm3(Predicted) |
| Melting Point | 113.5 °C(Solv: ethanol, 95% (64-17-5)) |
| Boling Point | 328.7±22.0 °C(Predicted) |
| Flash Point | 152.6°C |
| Vapor Presure | 0.000186mmHg at 25°C |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Sensitive | Lachrymatory |
| Refractive Index | 1.649 |
2-Bromo-4'-iodoacetophenone - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Hazard Note | Corrosive/Lachrymatory/Keep Cold |
2-Bromo-4'-iodoacetophenone - Introduction
2-Bromo-4 '-iodoacetophenone is an organic compound with the chemical formula C8H5BrIO. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-Bromo-4 '-iodoacetophenone is a yellow to orange crystal or crystal powder.
-Solubility: It is soluble in organic solvents, such as ethanol, ketone and dichloromethane, but almost insoluble in water.
-Melting point: Its melting point is about 70-75 degrees Celsius.
Use:
- 2-Bromo-4 '-iodoacetophenone can be used as an important intermediate in organic synthesis.
-It can be used to synthesize various initiators, pharmaceuticals and pesticides and other organic compounds.
Method:
A method for synthesizing 2-Bromo-4 '-iodoacetophenone is through the coupling reaction of Iodo and bromoacetophenone. The specific steps are as follows:
1. Under alkaline conditions, iodoacetophenone reacts with magnesium bromide to generate bromoacetophenone.
2.2-Bromo-4 '-iodoacetophenone can be synthesized by reacting bromoacetophenone with sodium iodide.
Safety Information:
- 2-Bromo-4 '-iodoacetophenone should be used and stored to avoid contact with eyes, skin and mucous membranes.
-Wear appropriate personal protective equipment such as protective gloves, glasses and lab coats when operating.
-The compound may be harmful to the environment and should be avoided from entering water and soil.
-For specific safety guidelines and handling methods, please refer to the safety data sheet (SDS) of the compound and the safety procedures for related chemicals.
Nature:
-Appearance: 2-Bromo-4 '-iodoacetophenone is a yellow to orange crystal or crystal powder.
-Solubility: It is soluble in organic solvents, such as ethanol, ketone and dichloromethane, but almost insoluble in water.
-Melting point: Its melting point is about 70-75 degrees Celsius.
Use:
- 2-Bromo-4 '-iodoacetophenone can be used as an important intermediate in organic synthesis.
-It can be used to synthesize various initiators, pharmaceuticals and pesticides and other organic compounds.
Method:
A method for synthesizing 2-Bromo-4 '-iodoacetophenone is through the coupling reaction of Iodo and bromoacetophenone. The specific steps are as follows:
1. Under alkaline conditions, iodoacetophenone reacts with magnesium bromide to generate bromoacetophenone.
2.2-Bromo-4 '-iodoacetophenone can be synthesized by reacting bromoacetophenone with sodium iodide.
Safety Information:
- 2-Bromo-4 '-iodoacetophenone should be used and stored to avoid contact with eyes, skin and mucous membranes.
-Wear appropriate personal protective equipment such as protective gloves, glasses and lab coats when operating.
-The compound may be harmful to the environment and should be avoided from entering water and soil.
-For specific safety guidelines and handling methods, please refer to the safety data sheet (SDS) of the compound and the safety procedures for related chemicals.
Last Update：2024-04-09 02:00:45
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