2-chloro-4'-fluorobenzophenone
2-chloro-4'-fluorobenzophenone
CAS: 1806-23-1
Molecular Formula: C13H8ClFO
2-chloro-4'-fluorobenzophenone - Names and Identifiers
| Name | 2-chloro-4'-fluorobenzophenone |
| Synonyms | 2,4'-CFBP 2-Chloro-4'-fluorobe 4'-FLUORO-2-CHLOROBENZOPHENONE 2-Chloro-4-Fluoro Benzophenone 2-chloro-4'-fluorobenzophenone 2-CHLORO-4'-FLUOROBENZOPHENONE 2-Chloro-4'-fluorobenzophenone (2-Chlorophenyl)(4-fluorophenyl)methanone (2-chlorophenyl)(4-fluorophenyl)-methanon (2-chlorophenyl)(4-fluorophenyl)methanone |
| CAS | 1806-23-1 |
| EINECS | 217-300-4 |
| InChI | InChI=1/C13H8ClFO/c14-12-4-2-1-3-11(12)13(16)9-5-7-10(15)8-6-9/h1-8H |
2-chloro-4'-fluorobenzophenone - Physico-chemical Properties
| Molecular Formula | C13H8ClFO |
| Molar Mass | 234.65 |
| Density | 1.277±0.06 g/cm3(Predicted) |
| Melting Point | 60-62°C |
| Boling Point | 337.3±22.0 °C(Predicted) |
| Flash Point | 157.8°C |
| Vapor Presure | 0.000106mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.577 |
| MDL | MFCD00000559 |
| Physical and Chemical Properties | 4-fluoro-2 ′-chlorobenzophenone is a colorless solid, m.p.60 ~ 62 ℃, insoluble in water, soluble in benzene, toluene, ketone and other organic solvents. |
2-chloro-4'-fluorobenzophenone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 21 - Harmful in contact with skin |
| Safety Description | 28 - After contact with skin, wash immediately with plenty of soap-suds. |
| Hazard Note | Irritant |
2-chloro-4'-fluorobenzophenone - Reference Information
| chemical properties | 4-fluoro-2 '-chlorobenzophenone is a colorless solid, m.p.60 ~ 62 ℃, insoluble in water, soluble in benzene, toluene, ketone and other organic solvents. |
| Use | 4-fluoro-2 ′-chlorobenzone is an intermediate of the fungicide fluphenicol. |
| production method | its preparation method is to place fluorobenzene and anhydrous aluminum trichloride in a reaction kettle, add 2-chlorobenzoyl chloride dropwise at low temperature, stir at the same time, heat up to reflux after dropping, continue the reaction for several hours, cool to room temperature and add HCl dropwise, control pH = 3~4, stratification, drying and distillation of the oil layer to obtain 4-fluoro-2-chlorobenzophenone. |
| EPA chemical information | information provided by: ofmpub.epa.gov (external link) |
Last Update：2024-04-09 15:16:36
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