中文名 | 2-甲基-3-羟基-4,5-二羟甲基吡啶 |
英文名 | Pyridoxine |
别名 | 吡多醇 吡哆素 吡多辛 吡哆醇 吡多素 维生素B6 食品级维生素B6 吡哆素,维生素 B6 5-羟基-6-甲基-3,4-吡啶二甲醇 2-甲基-3-羟基-4,5-二羟甲基吡啶 |
英文别名 | VB6 PYRIDOXIN PYRIDOXOL Vitamin B6 Pyridoxine 3-hydroxy-2-picoline-5-dimethanol 2-Picoline-4,5-dimethanol, 3-hydroxy- 3-Hydroxy-4,5-dimethylol-alpha-picoline 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl- 4,5-BIS(HYDROXYMETHYL)-2-METHYL-3-PYRIDINOL 4,5-BIS-HYDROXYMETHYL-2-METHYL-PYRIDIN-3-OL 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine 2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine |
CAS | 65-23-6 12001-77-3 |
EINECS | 200-603-0 |
化学式 | C8H11NO3 |
分子量 | 169.18 |
InChI | InChI=1/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3 |
InChIKey | LXNHXLLTXMVWPM-UHFFFAOYSA-N |
密度 | 1.2435 (rough estimate) |
熔点 | 214-215°C(lit.) |
沸点 | 298.46°C (rough estimate) |
溶解度 | H2O: 0.1g/mL,20 °C,澄清,无色 |
折射率 | 1.5100 (estimate) |
酸度系数 | pKa 5.00(H2Ot = 25.0I = 0.15(mixed)) (Uncertain) |
存储条件 | Inert atmosphere,2-8°C |
稳定性 | 稳定。与强氧化剂不相容。 |
敏感性 | Sensitive to light |
外观 | 固体 |
颜色 | White to Off-White |
物化性质 | 针状结晶(丙酮)。m.p.160℃ ,易升华,LD50(大鼠经口)4000mg/kg。 |
MDL号 | MFCD00012807 |
危险品标志 | Xi - 刺激性物品 |
风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36 - 穿戴适当的防护服。 |
WGK Germany | 3 |
RTECS | UV1350000 |
FLUKA BRAND F CODES | 8-10 |
海关编号 | 29362500 |
上游原料 | 草酸 纯碱 三乙胺 盐酸 |
下游产品 | 1,3-二氢-6-甲基呋喃并[3,4-C]吡啶-7-醇 |
参考资料 展开查看 | 1. 刘跃芹, 吴延东, 赵雪松,等. 高效液相色谱法测定酵母浸粉中维生素B_6的含量[J]. 食品工业, 2015(04):258-260. 2. 王月娥, 李东霞, 李智,等. 基于四峰超材料THz传感器的B族维生素检测[J]. 光谱学与光谱分析, 2020, v.40(06):131-136. 3. 陈银彬 王玉芳 侯志芳 等. Rg1联合B族维生素对急性心肌缺血小鼠NO释放及Rg1入脑量的影响[J]. 特产研究 2016(1):5-8. 4. 文鹏程, 崔娜, 梁琪,等. 牦牛初乳及其过渡乳中维生素变化规律的研究[J]. 食品工业科技, 2014, 35(16):121-121. 5. 郭刚军, 胡小静, 徐荣,等. 干燥方式对辣木叶营养,功能成分及氨基酸组成的影响[J]. 食品科学, 2018, 39(011):39-45. 6. Zheng, Peihe, et al. "Influence of B-complex vitamins on the pharmacokinetics of ginsenosides Rg1, Rb1, and Ro after oral administration." Journal of medicinal food 20.11 (2017): 1127-1132.https://doi.org/10.1089/jmf.2017.3922 7. [IF=6.06] Yin Bin Chen et al."Effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after oral administration."J Ginseng Res. 2017 Apr;41:209 8. [IF=2.786] Peihe Zheng et al."Influence of B-Complex Vitamins on the Pharmacokinetics of Ginsenosides Rg1, Rb1, and Ro After Oral Administration."J Med Food. 2017 Nov;20(11):1127-1132 9. [IF=7.514] Wei-Yu Mu et al."Determination of melamine and melamine–Cu(II) complexes in milk using a DNA-Ag hydrocolloid as the sensor."Food Chem. 2020 May;311:125889 10. [IF=7.514] Hongcai Li et al."Study on the nutritional characteristics and antioxidant activity of dealcoholized sequentially fermented apple juice with Saccharomyces cerevisiae and Lactobacillus plantarum fermentation."Food Chem. 2021 Nov;363:130351 11. [IF=6.057] Zihua Wang et al."Electrochemical sensor based on magnetic nanohybrids of multiple phthalocyanine doped ferrites/CMWCNTs for detection of rosmarinic acid."Talanta. 2021 May;226:122165 12. [IF=4.472] Han Hui et al."Changes in Biothiol Levels Are Closely Associated with Alzheimer’s Disease."J Alzheimers Dis. 2021 Jan;82(2):527-540 |
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