中文名 | 醋酸甲羟孕酮 |
英文名 | Medroxyprogesterone Acetate |
别名 | 甲孕酮 甲羟孕酮酯 安宫黄体酮 乙酸羟甲孕酮 醋酸甲羟孕酮 甲羟孕酮乙酸酯 甲羟孕酮醋酸酯 醋酸甲羟孕酮酯 醋酸甲羟孕酮(GMP) 甲羟孕酮 17-乙酸酯 醋酸孕酮 (安宫黄体酮) 安宫黄体酮(醋酸甲羟孕酮) |
英文别名 | depo-provera Medroxyprogesterone Acetate medroxyprogesterone 17-acetate hydroxymethylprogesterone acetate 17-acetoxy-6-alpha-methylprogesterone 17-alpha-hydroxy-6-alpha-methylprogesteroneacetate 17-alpha-hydroxy-6-alpha-methyl-progesteronacetate 17a-hydroxy-6a-methyl-4-pregnene-3,20-dione acetate 17-(acetyloxy)-6-methyl-20-dion(6alpha)-pregn-4-ene- 17alpha-acetoxy-6-alpha-methylpregn-4-ene-3,20-dione (6-alpha)-17-(acetyloxy)-6-methylpreg-4-ene-3,20-dione 17-(acetyloxy)-6-methyl-(6-alpha)-pregn-4-ene-20-dione 17-hydroxy-6-alpha-methylpregn-4-ene-3,20-dioneacetate 17-alpha-hydroxy-6-alpha-methylpregn-4-ene-3,20-dioneacetate (17-acetyl-6,10,13-trimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-16-yl) acetate |
CAS | 71-58-9 |
EINECS | 200-757-9 |
化学式 | C24H34O4 |
分子量 | 386.52 |
InChI | InChI=1/C24H34O4/c1-13-10-17-18(23(4)8-6-16(27)11-19(13)23)7-9-24(5)20(17)12-21(28-15(3)26)22(24)14(2)25/h11,13,17-18,20-22H,6-10,12H2,1-5H3 |
密度 | 1.0346 (rough estimate) |
熔点 | 206-207°C(lit.) |
沸点 | 432.7°C (rough estimate) |
比旋光度 | D +61° (in chloroform) |
闪点 | 215°C |
水溶性 | <0.1 g/100 mL at 23 ºC |
蒸汽压 | 3.85E-10mmHg at 25°C |
溶解度 | 几乎不溶于水,易溶于二氯甲烷,溶于丙酮,微溶于乙醇 (96%) |
折射率 | 48 ° (C=1, Dioxane) |
存储条件 | Sealed in dry,2-8°C |
稳定性 | 稳定,但对空气和光敏感较弱。与强氧化剂不相容。 |
外观 | 整洁 |
颜色 | White |
Merck | 13,5817 |
BRN | 2066112 |
物化性质 | 熔点 206-207°C 水溶性 <0.1 g/100 mL at 23°C |
MDL号 | MFCD00010483 |
危险品标志 | Xn - 有害物品 |
风险术语 | R40 - 少数报道有致癌后果。 R48 - 长期接触严重危害健康。 |
安全术语 | S22 - 切勿吸入粉尘。 S36/37/39 - 穿戴适当的防护服、手套和护目镜或面具。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 |
WGK Germany | 3 |
RTECS | TU5010000 |
海关编号 | 29372390 |
上游原料 | 过氧乙酸 甲基溴化镁 |
下游产品 | 甲孕酮 |
参考资料 展开查看 | 1. [IF=7.514] Suo Decheng et al."Trace analysis of progesterone and 21 progestins in milk by ultra-performance liquid chromatography coupled with high-field quadrupole-orbitrap high-resolution mass spectrometry."Food Chem. 2021 Nov;361:130115 |
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