本品为D-(—)-吡喃果糖。按干燥品计算,含C6H1206应为 98.0%〜102.0%.
取本品2.0g ,加水20ml溶解后,加酚酞指示液3 滴与氢氧化钠滴定液(0.02mol/L)0.20ml,应显粉红色。
取本品5.0g ,加水10ml溶解后,溶液应澄清无色;如显色,与黄色或黄绿色1号标准比色液(通则0901第一法)比较,不得更深。
取本品0.50g,加水10ml溶解后,照紫外-可见分光光度法(通则0401),在284nm的波长处测定,吸光度不得过0.32。
取本品0.60g ,依法检査(通则0801),与标准氯化钠溶液6.0ml制成的对照液比较,不得更浓(0.01% ) 。
取本品2.0g ,依法检查(通则0802),与标准硫酸钾溶液2.0ml制成的对照液比较,不得更浓(0.01% ) 。
钡盐
取本品10. 0g,加水溶解并稀释至100ml,作为贮备液。取贮备液10ml,加lmol/L 硫酸溶液lml制成供试品溶液,立即与取贮备液10ml,加水lml制成的对照液比较,1小时后再次比较,均不得更浑浊。
取本品2.0g ,精密称定,加水20ml使溶解,加盐酸2 滴,加氨-氯化铵缓冲液(pH10.0)5m l和铬黑T 指示剂适量,用乙二胺四醋酸二钠滴定液(0.005mol/L)滴定至蓝色。消耗乙二胺四醋酸二钠滴定液(0.005mol/L)不得过 0.5ml。
取本品5.0g,加水10ml,摇匀,各取lml分别置甲、乙两支比色管中,甲管中加乙醇9ml,乙管中加水9ml,摇匀。甲管的乳光不得比乙管更强。
取本品,在70°C减压干燥4小时,减失重量不得过0.5 % (通则0831) 。
不得过0.1% (通则0841) 。
取本品5.Og,加水23ml溶解后,加醋酸盐缓冲液(pH 3.5)2ml,依法检査(通则0821第一法),含重金属不得过百万分之四。
取本品2.0g,加水5ml溶解后,加稀硫酸5ml和溴试液lml,置水浴上加热并浓缩至约5ml,放冷,加盐酸5ml与水适量使成28ml,依法检查(通则0822第一法),应符合规定(0.0001% ) 。
取本品,用0.1%无菌蛋白胨水溶解后,经薄膜过滤法处理,用0.1% 无菌蛋白胨水分次冲洗(每膜不少于100ml),以金黄色葡萄球菌为阳性对照菌,依法检查(通则1101),应符合规定。(供无菌分装用)
中文名 | D(-)-果糖 |
英文名 | D(-)-Fructose |
别名 | 果糖 左旋糖 D-果糖 D(-)-果糖 D-(-)-果糖 beta-D-果糖 |
英文别名 | HPC Fructose D-Levulose D-Fructose Fruit sugar D(-)-Fructose Fructopyranose fructose, pure Arabino-hexulose D-fructofuranose beta-D-fructopyranose b-D-Fructose (1.04007) D-(-)-Fructose for analysis |
CAS | 57-48-7 7660-25-5 |
EINECS | 200-333-3 |
化学式 | C6H12O6 |
分子量 | 180.157 |
InChI | InChI=1/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6?/m1/s1 |
密度 | 1.694g/cm3 |
熔点 | 119-122℃ (dec.) |
沸点 | 440.1°C at 760 mmHg |
比旋光度 | -92.25 º (c=10,H2O,on dry sub.) |
闪点 | 220°C |
水溶性 | 3750 g/L (20℃) |
蒸汽压 | 1.36E-09mmHg at 25°C |
溶解度 | 易溶于水,溶于甲醇(1g/14m1)和乙醇(1g/15m1),不溶于乙醚。 |
折射率 | 1.616 |
存储条件 | 2-8℃ |
敏感性 | Easily absorbing moisture |
外观 | 白色结晶性粉末 |
物化性质 | 熔点 119-122°C (dec.) 比旋光度 -92.25° (c=10,H2O,on dry sub.) 水溶性 3750 g/L (20°C) |
MDL号 | MFCD00148910 |
安全术语 | S24/25 - 避免与皮肤和眼睛接触。 |
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本品为D-(—)-吡喃果糖。按干燥品计算,含C6H1206应为 98.0%〜102.0%.
取本品2.0g ,加水20ml溶解后,加酚酞指示液3 滴与氢氧化钠滴定液(0.02mol/L)0.20ml,应显粉红色。
取本品5.0g ,加水10ml溶解后,溶液应澄清无色;如显色,与黄色或黄绿色1号标准比色液(通则0901第一法)比较,不得更深。
取本品0.50g,加水10ml溶解后,照紫外-可见分光光度法(通则0401),在284nm的波长处测定,吸光度不得过0.32。
取本品0.60g ,依法检査(通则0801),与标准氯化钠溶液6.0ml制成的对照液比较,不得更浓(0.01% ) 。
取本品2.0g ,依法检查(通则0802),与标准硫酸钾溶液2.0ml制成的对照液比较,不得更浓(0.01% ) 。
钡盐
取本品10. 0g,加水溶解并稀释至100ml,作为贮备液。取贮备液10ml,加lmol/L 硫酸溶液lml制成供试品溶液,立即与取贮备液10ml,加水lml制成的对照液比较,1小时后再次比较,均不得更浑浊。
取本品2.0g ,精密称定,加水20ml使溶解,加盐酸2 滴,加氨-氯化铵缓冲液(pH10.0)5m l和铬黑T 指示剂适量,用乙二胺四醋酸二钠滴定液(0.005mol/L)滴定至蓝色。消耗乙二胺四醋酸二钠滴定液(0.005mol/L)不得过 0.5ml。
取本品5.0g,加水10ml,摇匀,各取lml分别置甲、乙两支比色管中,甲管中加乙醇9ml,乙管中加水9ml,摇匀。甲管的乳光不得比乙管更强。
取本品,在70°C减压干燥4小时,减失重量不得过0.5 % (通则0831) 。
不得过0.1% (通则0841) 。
取本品5.Og,加水23ml溶解后,加醋酸盐缓冲液(pH 3.5)2ml,依法检査(通则0821第一法),含重金属不得过百万分之四。
取本品2.0g,加水5ml溶解后,加稀硫酸5ml和溴试液lml,置水浴上加热并浓缩至约5ml,放冷,加盐酸5ml与水适量使成28ml,依法检查(通则0822第一法),应符合规定(0.0001% ) 。
取本品,用0.1%无菌蛋白胨水溶解后,经薄膜过滤法处理,用0.1% 无菌蛋白胨水分次冲洗(每膜不少于100ml),以金黄色葡萄球菌为阳性对照菌,依法检查(通则1101),应符合规定。(供无菌分装用)
取本品10g,精密称定,置100ml量瓶中,加水适量与氨试液0.2ml,溶解后,用水稀释至刻度,摇匀,放置30分钟后,在25°C时,依法测定旋光度(通则0621),与1.124相乘,即得供试品中C6H12O6的重量(g)。
营养药。
密封,阴凉干燥处保存。
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