桑色素是黄酮类衍生物,为淡黄色或黄色针状结晶或无定形粉末。分子量302. 24,熔点299~300℃(分解)。有一水物、三水物和无水物三种存在形式。微溶于热水和碱性水溶液,可溶于乙醇,碱性条件下呈黄色或橙色,遇铁离子变色。天然品主要存在于南美黄木树和中国桑树的根、皮中。
黄木树的根或木质部分用乙醇浸泡提取后,再经精制而得。
可用作食品抗氧剂。
中文名 | 桑色素 |
英文名 | Morin hydrate |
别名 | 桑色素 铝离子载体 I 桑色素(五羟黄酮 桑色素(五羟黄酮,桑黄素) 桑色素, 来源于桑科植物的树皮 2',3,4',5,7-五羟基黄酮 MORIN HYDRATE 桑色素 MORIN HYDRATE 桑色素 标准品 五羟黄酮,桑黄素,2',3,4',5,7-五羟基黄酮 桑色素(五羟黄酮,桑黄素,2',3,4',5,7-五羟基黄酮) |
英文别名 | MORIN Morin Fustic FUSTIC CI 75660 C.I. 75660 CI NO 75660 Morin hydrate Morin dihydrate Morin (C.I. 75660) TIMTEC-BB SBB008853 C.I. Natural Yellow 8 2,3,4,5,7-Pentahydroxyflavone 3,5,7,2',4'-PENTAHYDROXYFLAVONE 2',3,4',5,7-PENTAHYDROXYFLAVONE 2-(3,5-dihydroxyphenyl)-3,6,8-trihydroxy-4H-chromen-4-one 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-on |
CAS | 480-16-0 |
EINECS | 207-542-9 |
化学式 | C15H10O7 |
分子量 | 302.24 |
InChI | InChI=1/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H |
InChIKey | YXOLAZRVSSWPPT-UHFFFAOYSA-N |
密度 | 1.3616 (rough estimate) |
熔点 | 299-300°C (dec.)(lit.) |
沸点 | 363.28°C (rough estimate) |
闪点 | 249.3°C |
水溶性 | 0.25g/L(20 ºC) |
蒸汽压 | 2.94E-17mmHg at 25°C |
溶解度 | 甲醇: 50mg/ml |
折射率 | 1.4790 (estimate) |
酸度系数 | 6.30±0.40(Predicted) |
存储条件 | under inert gas (nitrogen or Argon) at 2-8°C |
稳定性 | 稳定。与强氧化剂不相容。 |
外观 | 粉末 |
颜色 | yellow |
Merck | 6269 |
物化性质 | 黄色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于桑白皮,人参。 |
MDL号 | MFCD00006826 |
危险品标志 | Xi - 刺激性物品 T - 有毒物品 |
风险术语 | R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 R25 - 吞食有毒。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36 - 穿戴适当的防护服。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 |
危险品运输编号 | UN 2811 6.1 / PGIII |
WGK Germany | 3 |
RTECS | LK8749000 |
FLUKA BRAND F CODES | 8-10-23 |
海关编号 | 29329990 |
参考资料 展开查看 | 1. 孙莲 孟磊 勉强辉 等. HPLC同时测定新疆药桑枝中6种成分的含量[J]. 中国现代应用药学 2013 030(006):660-663. 2. 白淑玮, 李凤至, 姚倩. 桑色素对视网膜母细胞瘤生长和凋亡的影响[J]. 眼科, 2016(3):171-174. 3. Lyu, Yunbin, et al. "Identification and characterization of three flavonoid 3-O-glycosyltransferases from Epimedium koreanum Nakai." Biochemical Engineering Journal 163 (2020): 107759.https://doi.org/10.1016/j.bej.2020.107759 4. [IF=2.896] Lu Wang et al."Rapid assay for testing superoxide anion radical scavenging activities to natural pigments by ultra-high performance liquid chromatography-diode-array detection method."Anal Methods-Uk. 2015 Feb;7(4):1535-1542 5. [IF=9.811] Manjie Gao et al."High-Crystallinity Covalent Organic Framework Synthesized in Deep Eutectic Solvent: Potentially Effective Adsorbents Alternative to Macroporous Resin for Flavonoids."Chem Mater. 2021;33(20):8036–8051 6. [IF=7.514] Yuan Cheng et al."Dual effects of quercetin on protein digestion and absorption in the digestive tract."Food Chem. 2021 Oct;358:129891 7. [IF=6.023] Yajing Fang et al."Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells."Fo 8. [IF=5.833] Zhou Zhidu et al."Ultra-sensitive amperometric determination of quercetin by using a glassy carbon electrode modified with a nanocomposite prepared from aminated graphene quantum dots, thiolated β-cyclodextrin and gold nanoparticles."Microchim Acta. 2020 9. [IF=4.932] Qingyu Meng et al."Morin hydrate inhibits atherosclerosis and LPS-induced endothelial cells inflammatory responses by modulating the NFκB signaling-mediated autophagy."Int Immunopharmacol. 2021 Nov;100:108096 10. [IF=3.978] Yunbin Lyu et al."Identification and characterization of three flavonoid 3-O-glycosyltransferases from Epimedium koreanum Nakai."Biochem Eng J. 2020 Nov;163:107759 11. [IF=3.935] Jingyun Zheng et al."A systematic investigation on free phenolic acids and flavonoids profiles of commonly consumed edible flowers in China."J Pharmaceut Biomed. 2019 Aug;172:268 12. [IF=5.279] Yajing Fang et al."Transport and Interactions of Co-incubated Bi-functional Flavonoids through Inhibiting the Function of P-Glycoprotein (P-gp) Using KB/Multidrug-Resistant (MDR) Cells and Rat Everted Gut Sacs."J Agr Food Chem. 2022;70(6):1923–1933 13. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 14. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 15. [IF=2.863] Jue Cui et al."Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells."Food Science & Nutrition |
桑色素是黄酮类衍生物,为淡黄色或黄色针状结晶或无定形粉末。分子量302. 24,熔点299~300℃(分解)。有一水物、三水物和无水物三种存在形式。微溶于热水和碱性水溶液,可溶于乙醇,碱性条件下呈黄色或橙色,遇铁离子变色。天然品主要存在于南美黄木树和中国桑树的根、皮中。
黄木树的根或木质部分用乙醇浸泡提取后,再经精制而得。
可用作食品抗氧剂。
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