汉黄芩素
汉黄芩素(Wogonin)
CAS: 632-85-9
化学式: C16H12O5
| 中文名 | 汉黄芩素 |
| 英文名 | Wogonin |
| 别名 | 汉黄芩素 汉黄芩黄酮 汉黄芩素(分析标准品) 汉黄芩素, 来源于黄芩 WOGONIN 汉黄芩素 7-二羟基-8-甲氧基-2-苯基-4H-1-苯并呋喃-4-酮 5,7-二羟基-8-甲氧基-2-苯基-4H-1-苯并呋喃-4-酮 汉黄芩素(5,7-二羟基-8-甲氧基-2-苯基-4H-1-苯并呋喃-4-酮) |
| 英文别名 | WOGONIN Wogonin vogonin Wogonin 632-85-9 5,7-DIHYDROXY-8-METHOXYFLAVON 5,7-DIHYDROXY-8-METHOXYFLAVONE 5,7-dihydroxy-8-methoxy-2-phenyl-4H-chromen-4-one 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-on 5,7-dihydroxy-8-methoxy-2-phenyl-4h-1-benzopyran-4-one 5,7-Dihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one |
| CAS | 632-85-9 |
| EINECS | 1592732-453-0 |
| 化学式 | C16H12O5 |
| 分子量 | 284.26 |
| InChI | InChI=1/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8,17,19H,1H3 |
| InChIKey | XLTFNNCXVBYBSX-UHFFFAOYSA-N |
| 密度 | 1.420±0.06 g/cm3(Predicted) |
| 熔点 | 203-206°C |
| 沸点 | 518.8±50.0 °C(Predicted) |
| 闪点 | 198.3°C |
| 蒸汽压 | 2.21E-11mmHg at 25°C |
| 溶解度 | DMSO: ≥ 20 mg/mL |
| 折射率 | 1.668 |
| 酸度系数 | 6.83±0.40(Predicted) |
| 存储条件 | Inert atmosphere,2-8°C |
| 外观 | 黄色固体 |
| 颜色 | Light Yellow to Yellow |
| 最大波长(λmax) | ['319nm(EtOH)(lit.)'] |
| 物化性质 | 极易溶于甲醇、乙醇、丙酮和醋酸乙酯, 溶于乙醇、醋酸和氯仿, 微溶于苯和水, 不溶于二硫化碳和石油英。 来源于唇形科植物黄芩（Scutellaria baicalensis Georgi ）根 |
| MDL号 | MFCD00017736 |
| 安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| RTECS | LK8331000 |
| 海关编号 | 29329990 |
| 上游原料 | 白杨素 2,3,4-TRIMETHOXY-6-HYDROXYACETOPHENONE |
| 下游产品 | 千层纸素A |
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HPLC法测定芩杏清热止咳颗粒中8种成分[J]. 中成药 2019 041(005):995-999. 12. 柴冲冲 毛民 袁金凤 等. 不同方法软化切制后的黄芩饮片颜色与5种黄酮类成分含量的相关性研究[J]. 中国中药杂志 2019. 13. 柴冲冲,曹妍,毛民,王靖越,刘娜,李欣欣,张凯,陈东玲,魏龙吟,尹怡慧,李飞.基于电子舌技术评价黄芩酒炙前后滋味变化及其在黄芩饮片鉴别中的应用研究[J].中国中药杂志,2020,45(11):2552-2559. 14. 商利娜, 王亚静, 赵鑫,等. 基于谱-效关系探究黄芩抑制白色念珠菌的质量标志物[J]. 中成药, 2020, 042(005):1357-1361. 15. 李云静, 张建逵, 赵玥,等. 黄芩药材颜色及其有效成分的相关性[J]. 中国医药工业杂志, 2017(7). 16. 袁杰, 李锬, 周利,等. 基于超高效液相色谱法和色差仪法的黄芩药材质量评价[J]. 世界中医药, 2019. 17. 任永申, 邓鑫, 雷蕾,等. 基于抑菌效应成分指纹谱的黄芩质量评价研究[J]. 药学学报, 2019, 054(012):2155-2161. 18. 张慧, 李思雨, 冯宏玲,等. 基于效应成分指数的双黄连制剂质量控制研究[J]. 药学学报, 2019, 054(012):2149-2154. 19. 莉莉,陈勇,张蒙伟,鄢红霞,高守红,陈万生.UHPLC-MS/MS法测定新冠肺炎经验方寒湿郁肺汤中11种主成分的含量[J].药学实践杂志,2021,39(02):148-151+156. 20. Cheng, Yan, et al. "Controlled Extraction of Flavonoids From Radix Scutellariae by Subcritical Water." CLEAN–Soil, Air, Water 44.3 (2016): 299-303.https://doi.org/10.1002/clen.201300193 21. Sun, Chenglong, et al. "A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi." Journal of pharmaceutical and biomedical analysis 179 (2020): 113014.https://doi.org/10.1016/j.jpba.2019.11 22. Yanqiu, et al. "Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix. " Journal of pharmaceutical and biomedical analysis 164 23. Xu, Jun. "Improved approaches and strategies for analyzing decoctions of medicinal herbs." (2016). 24. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239 25. [IF=3.935] Yanqiu Gu et al."Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix."J Pharmaceut Biomed. 2019 Feb;164:550 26. [IF=3.361] Huanyu Guan et al."Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out 27. [IF=3.205] Zhuangzhuang Li et al."Simultaneous quantification of fifteen compounds in rat plasma by LC-MS/MS and its application to a pharmacokinetic study of Chaihu-Guizhi decoction."J Chromatogr B. 2019 Jan;1105:15 28. [IF=5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369 29. 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汉黄芩素 - 简介
性质：
汉黄芩素为黄色晶体粉末，具有苦味。它在水中稍溶，在醇和醚中溶解性较好。它的化学名称是5,6,7-三甲氧基黄蒿素。
用途： 它具有抗氧化、抗炎、抗菌、抗肿瘤、抗生殖系统疾病等作用。
制法：
汉黄芩素的制法主要是从汉黄芩中提取而来。通常的提取方法包括热水提取法、乙醇提取法、超声波提取法等。
安全信息：
汉黄芩素作为一种天然化合物，在一般使用情况下是相对安全的。个体耐受性可能存在差异，长期大量摄入可能引起消化系统不适。使用时应按照医生或药师的指导和适当剂量使用，避免过量使用。
最后更新：2024-04-09 20:47:21
供应商列表
提供多种规格现货供应
产品名: 汉黄芩素(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IW00101
产地: 北京
包装: 1ml/瓶
规格: IW00101-1ml
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库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
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提供多种规格现货供应
产品名: 汉黄芩素(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IW00101
产地: 北京
包装: 1ml/瓶
规格: IW00101-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
汉黄芩素的上游原料
4H-1-Benzopyran-4-one, 5,8-dihydroxy-2-phenyl-7-(phenylmethoxy)- 2,3,4-TRIMETHOXY-6-HYDROXYACETOPHENONE 肉桂酰氯
汉黄芩素的下游产品
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