以单宁形式存在于五倍子,槲树皮和茶叶中。白色或淡黄色针状晶体,或棱柱状晶体。有绢丝光泽,味微酸,具收敛性。在100 N120℃失去结晶水。溶于乙醇、丙酮、乙二醇,微溶于水、乙醚。相对密度1. 694。熔点251℃(分解)。
由五倍子单宁经加压水解后得双没食子酸,继续水解成没食子酸和葡萄糖。反应温度133~135℃,压力0. 1765~0.19 61MPa。
可制备焦性没食子酸、药物、墨水、媒介染料。检测游离无机酸、二羟基丙酮及生物碱等。还可用作显影剂及制取食品防腐剂没食子酸丙酯。还可制取防爆剂,用作分析化学试剂。
中文名 | 没食子酸单水合物 |
英文名 | Gallic acid monohydrate |
别名 | 一水没食子酸 单水没食子酸 没食子酸水合物 电子级没食子酸 没食子酸,一水 没食子酸,一水物 没食子酸单水合物 五倍子酸单水合物 没食子酸 一水合物 没食子酸一水化合物 没食子酸单水合物, ACS级 3,4,5-三羟基苯甲酸一水化物 3,4,5-三羟基苯甲酸一水化物,ACS 3,4,5-三羟基苯甲酸 一水化物, ACS 没食子酸-水合物 |
英文别名 | Gallic Acid, Hydrate GALLIC ACID, HYDRATE GALLIC ACID-1-HYDRATE Gallic Acid-1-Hydrate GALLIC ACID MONOHYDRATE Gallic acid monohydrate 3,4,5-Trihydroxybenzoate Gallic Acid(Monohydrate) 3,4,5-Trihydroxybenzoic Acid Hydrate Gallic Acid, Monohydrate, Crystal, Reagent, ACS |
CAS | 5995-86-8 |
EINECS | 611-919-7 |
化学式 | C7H8O6 |
分子量 | 188.13 |
InChI | InChI=1/C7H6O5.H2O/c8-4-1-3(7(11)12)2-5(9)6(4)10;/h1-2,8-10H,(H,11,12);1H2 |
InChIKey | IUTKPPDDLYYMBE-UHFFFAOYSA-N |
密度 | 1.694 |
熔点 | 252°C (dec.)(lit.) |
沸点 | 596.6°C at 760 mmHg |
闪点 | 250°C |
水溶性 | 15 g/l (20 ºC) |
蒸汽压 | 4.43E-15mmHg at 25°C |
溶解度 | 它可溶于乙醇、乙醚、甘油、丙酮,可忽微溶于苯、氯仿、石油醚。 |
存储条件 | Keep in dark place,Sealed in dry,Room Temperature |
稳定性 | 光敏 |
敏感性 | Hygroscopic |
外观 | 固体 |
颜色 | White to cream |
Merck | 14,4345 |
BRN | 2050274 |
物化性质 | 白色或淡黄色针状晶体,或棱柱状晶体。有绢丝光泽,味微酸。 溶于乙醇、丙酮、乙二醇,微溶于水、乙醚。 |
MDL号 | MFCD00149098 |
体外研究 | Gallic acid is an antioxidant which can inhibit both COX-2. After 18 h treatment with Gallic acid, the number of viable neutrophils is dramatically decreased from 40.3% to 27.7%, highly comparable with 26.4% for untreated neutrophils. Gallic acid fails to attenuate isoproterenol-induced myocytolysis. |
体内研究 | The food intake (2.6±0.08 g/day, p=0.69) and the body weight (2.5±0.69 g, p=0.76) of the Gallic acid group do not differ significantly from those of the control group (food intake; 2.41±0.14 g/day and the body weight; 2.83±0.84 g/day). The blood glucose tolerance in the Gallic acid group is significantly improved after 2 weeks of treatment. The blood glucose tolerance of the Gallic acid group after a treatment period of 2 weeks is also significantly better than that of the control group at 90 and 120 min ( p<0.05). The serum triglyceride concentration in the Gallic acid group (0.67±0.03 mM, p<0.05) is significantly reduced relative to that of the control group (1.08±0.20 mM). The total cholesterol concentration is similar in the control (3.19±0.27 mM) and Gallic acid (3.01±0.18 mM) groups. |
危险品标志 | Xi - 刺激性物品![]() |
风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
安全术语 | S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 S36 - 穿戴适当的防护服。 S24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 2 |
RTECS | LW7525000 |
FLUKA BRAND F CODES | 8-9-23 |
TSCA | Yes |
海关编号 | 29182900 |
下游产品 | 没食子酸 |
参考资料 展开查看 | 1. [IF=4.952] Jiayue Gao et al."Reduction of oil uptake in deep-fried apple slices by the combined ultrasonic and ethanol pre-treatment."Lwt Food Sci Technol. 2021 Dec;152:112274 2. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 |
以单宁形式存在于五倍子,槲树皮和茶叶中。白色或淡黄色针状晶体,或棱柱状晶体。有绢丝光泽,味微酸,具收敛性。在100 N120℃失去结晶水。溶于乙醇、丙酮、乙二醇,微溶于水、乙醚。相对密度1. 694。熔点251℃(分解)。
由五倍子单宁经加压水解后得双没食子酸,继续水解成没食子酸和葡萄糖。反应温度133~135℃,压力0. 1765~0.19 61MPa。
可制备焦性没食子酸、药物、墨水、媒介染料。检测游离无机酸、二羟基丙酮及生物碱等。还可用作显影剂及制取食品防腐剂没食子酸丙酯。还可制取防爆剂,用作分析化学试剂。
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