中文名 | 番泻草苷B |
英文名 | Sennoside B |
别名 | 番泻苷B 番泻叶苷B 番泻苷 B 番泻草苷B 番泻甙B,番卸苷B 番泻苷B(标准品) 番泻苷B(分析标准品) 番泻苷B(番泻草苷B, 番泻苷 B, 来源于番泻 番泻苷 BSENNOSIDE B SENNOSIDE B 番泻苷B |
英文别名 | NSC 112930 PURSENNIDE Sennoside B SENNOSIDE B(P) SENNIDINE B(RG) SENNOSIDE B(SH) UNII-F887D1637W Sennoside B std. 9,9-Bianthracene-2,2-dicarboxylic acid, 5,5-bis(.beta.-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-, (9R,9S)- (9R,9'S)-5,5'-bis(beta-D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid (9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid |
CAS | 128-57-4 |
EINECS | 204-895-0 |
化学式 | C42H38O20 |
分子量 | 862.74 |
InChI | InChI=1/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26+,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1 |
密度 | 1.3066 (rough estimate) |
熔点 | 209~212℃ |
沸点 | 698.48°C (rough estimate) |
比旋光度 | D20 -100° (c = 0.2 in 70% acetone); D20 -67° (c = 0.4 in 70% dioxane) |
闪点 | 348.6°C |
蒸汽压 | 0mmHg at 25°C |
溶解度 | DMSO (非常轻微,加热),甲醇 (轻微,加热) |
折射率 | 1.7630 (estimate) |
酸度系数 | 3.31±0.40(Predicted) |
存储条件 | 2-8°C |
稳定性 | 吸湿性 |
外观 | 整洁 |
颜色 | Light Yellow to Dark Yellow |
BRN | 5723747 |
物化性质 | 不溶于水、苯、乙醚、氯仿,微溶于甲醇、二苷醇-乙醚、丙酮、二氧六环,溶于碳酸氢钠水溶液。 来源于豆科植物狭叶番泻(Cassia angutifolia Vahl.)的荚 |
MDL号 | MFCD00151528 |
风险术语 | 22 - 吞食有害。 |
安全术语 | S22 - 切勿吸入粉尘。 S45 - 若发生事故或感不适,立即就医(可能的话,出示其标签)。 S24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
海关编号 | 29329990 |
参考资料 展开查看 | 1. 赵倩, 陈育鹏, 崔旭盛,等. 掌叶大黄UPLC多指标成分测定及指纹图谱研究[J]. 药物分析杂志, 2018, 038(010):1697-1710. 2. 罗山,黄王琛,刘懿,吕莹莹,李改元,唐文强.基于UPLC法泽泻水提液指纹图谱的建立[J].陕西农业科学,2021,67(01):49-52. 3. 陆杰,王婷婷,梁琨,安叡,王新宏,陈颖.UPLC-LTQ-Orbitrap-MS法分析大承气汤化学成分[J].中成药,2020,42(12):3275-3280. 4. 张明明. 大黄道地产区核心种质构建及优良种质筛选研究[D].北京中医药大学,2020. 5. Zhang, Wan-li, et al. "Establishment of a mouse model of cancer cachexia with spleen deficiency syndrome and the effects of atractylenolide I." Acta Pharmacologica Sinica 41.2 (2020): 237-248.https://doi.org/10.1038/s41401-019-0275-z 6. [IF=7.514] Li Yang et al."Color-reflected chemical regulations of the scorched rhubarb (Rhei Radix et Rhizoma) revealed by the integration analysis of visible spectrophotometry, Fourier transform infrared spectroscopy and high performance liquid chromatography."Food 7. [IF=3.361] Yanhui Zhao et al."Rapid characterization of the chemical constituents of Sanhua decoction by UHPLC coupled with Fourier transform ion cyclotron resonance mass spectrometry."Rsc Adv. 2020 Jul;10(44):26109-26119 8. [IF=4.098] Le Yang et al."Two-dimensional correlation spectroscopy indicates the infrared spectral markers of the optimum scorching degree of rhubarb (Rhei Radix et Rhizoma) to enhance the anti-inflammatory activity."Spectrochim Acta A. 2022 Apr;270:120853 9. [IF=5.645] Huilan Yue et al."Hypoglycemic ingredients identification of Rheum tanguticum Maxim. ex Balf. by UHPLC-triple-TOF-MS/MS and interrelationships between ingredients content and glycosidase inhibitory activities."Ind Crop Prod. 2022 Apr;178:114595 |
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