胶糖
氨基乙酸(Glycine)
CAS: 56-40-6
化学式: C2H5NO2
性质
白色或浅黄色针状结晶。味甜。溶于水，lOOg无水乙醇可溶该品约0. 06g,溶于164份吡啶，几乎不溶于乙醚。
制法
将氨水和碳酸铵混合并在水浴上加热，另配制氯乙酸水溶液，滴加上述混合液中，将混合物加热保温后，冷却结晶得到粗品。将粗品溶于沸水，加入甲醇，经结晶即得纯品甘氨酸。
用途
用于检验铜、金、银的试剂。还用于制药工业、生化研究、组织培养基的制各、营养增补剂等方面。
安全性
几乎无毒，豚鼠，经口服，致死量LD 6.8～8. Og/kg。遮光，密闭保存。
| 中文名 | 氨基乙酸 |
| 英文名 | Glycine |
| 别名 | 胶糖 甘氨酸 甘胺酸 氨基醋酸 氨基乙酸 L-甘氨酸 甘氨酸(医药级) 氨基乙酸 食品级 甘氨酸(氨基乙酸) 氨基乙酸(医药级) 甘氨酸 (GLY)溶液,100PPM |
| 英文别名 | Gly Glycine H-Gly-OH glycocoll L-Glycine Glycine BP GLYCINE USP BLOTTING BUFFER Aminoacetic acid GLYCINE TECHNICAL Glycine, Free Base USP24 GLYCINE USP24 Glycine (Food Grade) Glycine (Feed Grade) Glycine (Tech Grade) Glycine (Pharm Grade) |
| CAS | 56-40-6 |
| EINECS | 200-272-2 |
| 化学式 | C2H5NO2 |
| 分子量 | 75.07 |
| InChI | InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5) |
| InChIKey | DHMQDGOQFOQNFH-UHFFFAOYSA-N |
| 密度 | 1.595 |
| 熔点 | 240 °C (dec.) (lit.) |
| 沸点 | 233°C |
| 闪点 | 176.67°C |
| 水溶性 | 25 g/100 mL (25 ºC) |
| 蒸汽压 | 0.0000171 Pa (25 °C) |
| JECFA Number | 1421 |
| 溶解度 | H2O: 100 mg/mL |
| 折射率 | 1.4264 (estimate) |
| 酸度系数 | 2.35(at 25℃) |
| PH值 | 4(0.2 molar aqueous solution) |
| 存储条件 | 2-8°C |
| 稳定性 | 稳定。可燃。与强氧化剂不相容。 |
| 外观 | 粉末 |
| 颜色 | <5 (200mg/mL)(APHA) |
| 气味 | Odorless |
| 最大波长(λmax) | ['λ: 260 nm Amax: 0.05', , 'λ: 280 nm Amax: 0.05'] |
| Merck | 14,4491 |
| BRN | 635782 |
| 物化性质 | 白色单斜晶系或六方晶系晶体，或白色结晶粉末。无臭，有特殊甜味。 易溶于水，在水中的溶解度：25℃时为25g/100ml；50℃时为39.1g/100ml；75℃时为54.4g/100ml；100℃时为67.2g/100ml。极难溶于乙醇，在100g无水乙醇中约溶解0.06g。几乎不溶于丙酮和乙醚。 |
| MDL号 | MFCD00008131 |
| 风险术语 | 33 - 有累积效应的危险品。 |
| 安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 2 |
| RTECS | MB7600000 |
| TSCA | Yes |
| 海关编号 | 29224910 |
| 上游原料 | 甲醇 一氯乙酸 |
| 下游产品 | 二甲氧基甲烷 草甘膦 甲砜霉素 |
| 参考资料 展开查看 | 1. 吕雅琼 张冬梅 格日勒图. 乌珠穆沁羊生长过程中肌内结缔组织中Ⅰ型胶原蛋白变化研究[J]. 农产品加工·学刊(中) 2013(15):18-21. 2. WU Qiong 吴琼 Lü Ya-qiong 等. 乌珠穆沁羊生长过程中肌内结缔组织中Ⅲ型胶原蛋白的变化[C]// 中国肉类科技大会. 中国畜产业加工研究会 2014. 3. 黄威娜 杨勇 林苗. 分光光度法测定丝肽液中氨基酸总含量[J]. 香料香精化妆品 2011 000(003):35-38. 4. 葛淑华 赵丹丹 赵玖永 等. 利用含铬革屑制备液体冲施肥前驱体[J]. 皮革与化工 2017 34(005):15-20. 5. 李志强, 杜盼盼, 武慧欣,等. 孕鼠常见微波暴露对仔鼠行为发育及认知的影响[J]. 环境与职业医学, 2018, 035(005):438-442. 6. 胡坪君, 罗美霞, 陈柏忠,等. 新会柑酵素成分综合测定[J]. 中国医院药学杂志, 2018, 038(005):496-499. 7. 赵笑蕾, 杨锋, 张晓. 水力空化对蛋清蛋白功能特性的影响[J]. 食品科技, 2019, v.44;No.336(10):111-115. 8. 吴仪凡, 葛武鹏, 刘凯茹,等. 绵羊乳与其他乳种营养成分及乳清蛋白组分差异性分析[J]. 乳业科学与技术, 2019. 9. 王小琴, 邹玉安, 薛茜,等. 缺血预处理对大鼠脑组织及血清氨基酸水平的影响[J]. 山东医药, 2016, 56(010):31-32. 10. 张宁, 边育红, 张嘉丽,等. 羊胎盘肽对L6成肌细胞增殖能力和ATP浓度的影响[J]. 天津中医药大学学报, 2018, 37(006):488-493. 11. 王小琴, 邹玉安, 郭春燕,等. 脑缺血预处理对大鼠脑组织中氨基酸及肿瘤坏死因子－α含量的影响[J]. 中国临床药理学杂志, 2016, 32(005):424-426. 12. 陈一萌, 唐善虎, 李思宁,等. 超声波辅助木瓜蛋白酶及发酵处理对牦牛肉的理化和质构特性[J]. 食品与发酵工业, 2019(23). 13. 梁浩明, 龙晓英, 卢耀文,等. 鼻吸入薄荷油对小鼠精神疲劳行为及脑内氨基酸类神经递质的影响[J]. 中药新药与临床药理, 2015(05):649-654. 14. 王贺 曹文红 章超桦 等. UV-C辐照对凡纳滨对虾虾头主要内源酶酶学性质的影响[J]. 食品与发酵工业 2019 v.45;No.391(19):36-41. 15. 侯丽娟 严超 齐晓茹 王颉. 不同品种红枣酿制枣酒的香气差异性研究[J]. 食品工业 2017(5):208-212. 16. 李婉斯, 李婷, 陆春怡,等. 基于HPLC指纹图谱及聚类分析评价市售阿胶的质量[J]. 上海中医药大学学报, 2017, 031(006):91-96. 17. 祝洪艳, 张荻, 张力娜,等. 柱前衍生化HPLC法检测紫苏子和紫苏叶中氨基酸的含量[J]. 药物分析杂志, 2017(10):1858-1864. 18. 马桂芝,陈雪珊,蒋思思,段霞.柱前衍生HPLC-UV法测定类风湿性关节炎大鼠尿样中16种氨基酸含量[J].新疆医科大学学报,2018,41(08):1001-1005. 19. 王婷婷,郜玉钢,臧埔,赵岩,何忠梅,祝洪艳,张连学.复方麦鹿芪人参制剂主要成分变化及其在肝癌H22荷瘤小鼠体内的抗肿瘤作用[J].吉林大学学报(医学版),2017,43(04):698-704+858-859. 20. 宫瑞泽 赵卉 曲迪 等. 不同产地加工及炮制方法对鹿茸中胶原蛋白含量的影响[J]. 食品科学 2019(22). 21. 王胜超 张振凌 于文娜 等. 人中黄的HPLC指纹图谱及炮制机理初探[J]. 中药材 2017(05):83-87. 22. 张喜峰, 徐莹, 尚琪,等. 锁阳原花青素对葡萄糖/甘氨酸模拟体系糖基化终产物的抑制效果[J]. 天然产物研究与开发, 2019, 31(04):130-136+170. 23. 马长中, 罗章, 辜雪冬. 林芝砖红绒盖牛肝菌的营养成分分析及评价[J]. 食品科学, 2016, 37(024):124-129. 24. 陈思, 郜玉钢, 臧埔,等. 鹿角脱盘及其5种提取部位21种氨基酸含量对比分析[J]. 药物分析杂志, 2017(10):1851-1857. 25. 严超, 侯丽娟, 齐晓茹,等. 红枣白兰地发酵过程中酒醅氨基酸和有机酸的变化分析[J]. 食品工业科技, 2017, 38(014):121-125. 26. 李圆圆, 田晨颖, 刘晓美,等. 添加微量元素对黑豆发芽过程中成分的影响[J]. 食品工业科技, 2019, 40(09):104-110. 27. 张喜峰, 刘晓燕, 马银山,等. 黑果枸杞多酚的糖析萃取及其抑制糖基化终产物[J]. 精细化工, 2018, 035(003):395-401. 28. 姜鹏, 孙言才, 蔡颖,等. 基于超高效液相色谱-高分辨质谱联用技术研究苦参醇提物致大鼠肝毒性的尿液代谢组[J]. 安徽中医药大学学报, 2018. 29. 唐何娜, 杨磊, 欧阳志远,等. 基于体外仿生的海水珍珠矿化机制初步研究[J]. 电子显微学报, 2017, 036(006):589-597. 30. 王蓉蓉,胡争艳,吴平谷,单乐天,黄家卫,王春雷.超高效液相-串联质谱分析法同时测定蕲蛇提取物中核苷及氨基酸的含量[J].中国卫生检验杂志,2020,30(15):1793-1797+1803. 31. Yuanyuan Zhang, Zihan Pan, Chuan Rong, Yanan Shao, Yinghui Wang, Kefu Yu, Transformation of antibacterial agent roxithromycin in sodium hypochlorite disinfection process of different water matrices, Separation and Purification Technology, Volume 212, 2019, 32. Rong, Chuan, et al. "Formation of disinfection byproducts from sulfamethoxazole during sodium hypochlorite disinfection of marine culture water." Environmental Science and Pollution Research 25.33 (2018): 33196-33206.https://doi.org/10.1007/s11356-018-3278 33. Liu, Shaoying, et al. "Evaluation of selected plant growth regulators and fungicide residues in fruits for dietary risk assessment." Human and Ecological Risk Assessment: An International Journal 22.6 (2016): 1386-1395.https://doi.org/10.1080/10807039.2016 34. Zhongqian Song, Fengyu Quan, Yuanhong Xu, Mengli Liu, Liang Cui, Jingquan Liu, Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione, Carbon, Volume 10 35. Cai, Yawen, et al. "Fabrication of a phosphorylated graphene oxide–chitosan composite for highly effective and selective capture of U (VI)." Environmental Science: Nano 4.9 (2017): 1876-1886.https://doi.org/10.1039/C7EN00412E 36. Ji, Youan, et al. "Highly efficient separation of indole from model wash oil using tetraethyl ammonium amino acid ionic liquids." Separation and Purification Technology 258 (2021): 117997.https://doi.org/10.1016/j.seppur.2020.117997 37. Xiaokui Huo, Xiangge Tian, Yannan Li, Lei Feng, Yonglei Cui, Chao Wang, Jingnan Cui, Chengpeng Sun, Kexin Liu, Xiaochi Ma, A highly selective ratiometric fluorescent probe for real-time imaging of β-glucuronidase in living cells and zebrafish, Sensors and 38. Zhao, Zheng, et al. "Cholinium amino acids-glycerol mixtures: New class of solvents for pretreating wheat straw to facilitate enzymatic hydrolysis." Bioresource technology 245 (2017): 625-632.https://doi.org/10.1016/j.biortech.2017.08.209 39. [IF=9.594] Zhongqian Song et al."Multifunctional N,S co-doped carbon quantum dots with pH- and thermo-dependent switchable fluorescent properties and highly selective detection of glutathione."Carbon. 2016 Aug;104:169 40. [IF=7.46] Xiaokui Huo et al."A highly selective ratiometric fluorescent probe for real-time imaging of β-glucuronidase in living cells and zebrafish."Sensor Actuat B-Chem. 2018 Jun;262:508 41. [IF=6.079] Tian Luo et al."Determination of underivatized amino acids to evaluate quality of beer by capillary electrophoresis with online sweeping technique."J Food Drug Anal. 2017 Oct;25:789 42. [IF=4.952] Fengfeng Qu et al."Effect of different drying methods on the sensory quality and chemical components of black tea."Lwt Food Sci Technol. 2019 Jan;99:112 43. [IF=4.411] Yujiao Hua et al."Quality Evaluation of Pseudostellariae Radix Based on Simultaneous Determination of Multiple Bioactive Components Combined with Grey Relational Analysis."Molecules. 2017 Jan;22(1):13 44. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254 45. [IF=3.535] Tian Luo et al."Establishing a sensitive capillary electrophoresis-UV method for direct determination of amino acids to evaluate vinegar quality."Electrophoresis. 2018 Jun;39(11):1410-1416 46. [IF=2.896] Jing Ke et al."Development of a gradient micellar liquid chromatographic method eluting from micellar mode to high submicellar mode for the rapid separation of free amino acids."Anal Methods-Uk. 2017 Mar;9(11):1762-1770 47. [IF=2.896] Ya-yun Chen et al."Determination of free amino acids and nucleosides and nucleobases in Annona squamosa L. fruitages from different regions in China by LC-QTRAP-MS/MS."Anal Methods-Uk. 2017 Jun;9(25):3862-3869 48. [IF=2.727] Tian Luo et al."Quality assessment of soy sauce using underivatized amino acids by capillary electrophoresis."International Journal Of Food Properties. 2018 Jan 08 49. [IF=11.413] Zhenhao Tian et al."A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor."Acta Pharm Sin B. 2021 Jun;: 50. [IF=7.79] Ye Lu et al."Enhancing hydrogel-based long-lasting chemiluminescence by a platinum-metal organic framework and its application in array detection of pesticides and D-amino acids."Nanoscale. 2020 Feb;12(8):4959-4967 51. [IF=7.514] Chi Zhang et al."Identification of soybean peptides and their effect on the growth and metabolism of Limosilactobacillus reuteri LR08."Food Chem. 2022 Feb;369:130923 52. [IF=6.986] Xiangge Tian et al."Visual High-Throughput Screening for Developing a Fatty Acid Amide Hydrolase Natural Inhibitor Based on an Enzyme-Activated Fluorescent Probe."Anal Chem. 2020;92(14):9493–9500 53. [IF=6.785] Xiangge Tian et al."Endoplasmic Reticulum Targeting Ratiometric Fluorescent Probe for Carboxylesterase 2 Detection in Drug-Induced Acute Liver Injury."Anal Chem. 2019;91(24):15840–15845 54. [IF=4.952] Huan Zhang et al."Label-free quantification proteomics reveals the active peptides from protein degradation during anaerobic fermentation of tea."Lwt Food Sci Technol. 2021 Oct;150:111950 55. [IF=4.821] Yixin Nie et al."Nitrogen-rich quantum dots-based fluorescence molecularly imprinted paper strip for p-nitroaniline detection."Microchem J. 2019 Jul;148:162 56. [IF=4.821] Peng Wan et al."Analysis of aroma-active compounds in bighead carp head soup and their influence on umami of a model soup."Microchem J. 2021 Sep;168:106436 57. [IF=4.616] Ling Li et al."Point-of-care testing of melamine via gas pressure readout using polythymine-coated Au@Pt nanoparticles through specific triple hydrogen-bonding recognition."Analyst. 2021 Sep;146(19):5898-5903 58. [IF=4.556] Dandan Zhao et al."Physico-chemical properties and free amino acids profiles of six wolfberry cultivars in Zhongning."J Food Compos Anal. 2020 May;88:103460 59. [IF=4.451] Chi Zhang et al."Effects of soybean protein isolates and peptides on the growth and metabolism of Lactobacillus rhamnosus."J Funct Foods. 2021 Feb;77:104335 60. [IF=4.379] Feng Lin et al."Chemical profile changes during pile fermentation of Qingzhuan tea affect inhibition of α-amylase and lipase."Sci Rep-Uk. 2020 Feb;10(1):1-10 61. [IF=4.204] Zhu Mingyue et al."A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living cells and tissues."Frontiers of Chemical Science and Engineering. 2021 Jun 29 62. [IF=4.142] Qu Fei et al."Ratiometric detection of alkaline phosphatase based on aggregation-induced emission enhancement."Anal Bioanal Chem. 2019 Nov;411(28):7431-7440 63. [IF=4.142] Li Cong et al."A fluorescence strategy for monitoring α-glucosidase activity and screening its inhibitors from Chinese herbal medicines based on Cu nanoclusters with aggregation-induced emission."Anal Bioanal Chem. 2021 Apr;413(9):2553-2563 64. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697 65. [IF=3.361] Furong Wang et al."Effect of free amino acids and peptide hydrolysates from sunflower seed protein on the formation of pyrazines under different heating conditions."Rsc Adv. 2021 Aug;11(45):27772-27781 66. [IF=3.167] Fuli Sun et al."Aqueous Preparation of Maillard Reaction Intermediate from Glutathione and Xylose and its Volatile Formation During Thermal Treatment."J Food Sci. 2019 Dec;84(12):3584-3593 67. [IF=2.097] Ke Jing et al."Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acids."Chem Pap. 2019 Oct;73(10):2417-2426 68. [IF=1.618] Wang Shengnan et al."Simultaneous Determination of Iridoid Glycosides, Phenylpropanoid Glycosides, Organic Acids, Nucleosides and Amino Acids in Scrophulariae Radix Processed by Different Processing Methods by HPLC-QTRAP-MS/MS."J Chromatogr Sci. 2021 Jun; 69. [IF=4.242] Hang Yang et al."Dietary leucine requirement of juvenile largemouth bass (Micropterus salmoides) based on growth, nutrient utilization and growth-related gene analyses."Aquaculture. 2022 Jun;555:738207 70. [IF=6.321] Guangqu Liu et al."Multivesicular Liposomes for Glucose-Responsive Insulin Delivery."Pharmaceutics. 2022 Jan;14(1):21 71. [IF=7.312] Chao Wu et al."Mixed matrix membrane comprising glycine grafted CuBTC for enhanced CO2 separation performances with excellent stability under humid atmosphere."SEPARATION AND PURIFICATION TECHNOLOGY. 2022 Aug;295:121287 72. [IF=4.821] Shi Sen Ding et al."Synergistic effect-mediated fluorescence switching of nitrogen-doped carbon dots for visual detection of alkaline phosphatase."MICROCHEMICAL JOURNAL. 2022 Oct;181:107651 73. [IF=3.463] Xiaomei Dai et al."S-alk(en)ylcysteine sulfoxides biosynthesis and free amino acids profile in different parts of postharvest chive (Allium schoenoprasum L.)."SCIENTIA HORTICULTURAE. 2022 Sep;303:111191 74. [IF=6.057] Supan Cheng et al."Liquid crystal-based sensitive and selective detection of uric acid and uricase in body fluids."Talanta. 2022 Jul;244:123455 |
胶糖 - 性质
可信数据
白色或浅黄色针状结晶。味甜。溶于水，lOOg无水乙醇可溶该品约0. 06g,溶于164份吡啶，几乎不溶于乙醚。
最后更新：2024-01-02 23:10:35
胶糖 - 制法
可信数据
将氨水和碳酸铵混合并在水浴上加热，另配制氯乙酸水溶液，滴加上述混合液中，将混合物加热保温后，冷却结晶得到粗品。将粗品溶于沸水，加入甲醇，经结晶即得纯品甘氨酸。
最后更新：2022-01-01 09:26:22
胶糖 - 用途
可信数据
用于检验铜、金、银的试剂。还用于制药工业、生化研究、组织培养基的制各、营养增补剂等方面。
最后更新：2022-01-01 09:26:22
胶糖 - 安全性
可信数据
几乎无毒，豚鼠，经口服，致死量LD 6.8～8. Og/kg。遮光，密闭保存。
最后更新：2022-01-01 11:10:00
胶糖 - 简介
氨基乙酸。以下是关于氨基乙酸的性质、用途、制法和安全信息的介绍：
性质：
氨基乙酸可溶于水，并易与其他有机溶剂混溶。
它具有弱酸性，能够与碱反应生成相应的盐类。
氨基乙酸有一定的挥发性，故在室温下可闻到其特殊的气味。
用途：
氨基乙酸常用作金属加工液中的缓蚀剂，能够与金属表面形成一层保护膜，减少金属的腐蚀。
它还可用于纤维素和纺织品的漂白及染色工艺中，作为脱色剂和活性染料的稳定剂。
制法：
氨基乙酸通常通过乙醇胺和氯乙酸反应制得。反应可在常温下进行，生成氨基乙酸和氯化氢，后者可通过进一步处理得到氯化物和水。
安全信息：
氨基乙酸为刺激性物质，请避免直接接触皮肤和眼睛，使用时应佩戴防护手套和护目镜。
避免吸入其蒸气，应保持通风良好的工作环境。
如不慎摄入或发生吸入过量，应立即寻求医疗救助。
在储存和使用过程中，应远离高温和明火，避免与强氧化剂接触。
使用前请详细阅读并遵守产品的安全操作指南和相关法规。
性质：
氨基乙酸可溶于水，并易与其他有机溶剂混溶。
它具有弱酸性，能够与碱反应生成相应的盐类。
氨基乙酸有一定的挥发性，故在室温下可闻到其特殊的气味。
用途：
氨基乙酸常用作金属加工液中的缓蚀剂，能够与金属表面形成一层保护膜，减少金属的腐蚀。
它还可用于纤维素和纺织品的漂白及染色工艺中，作为脱色剂和活性染料的稳定剂。
制法：
氨基乙酸通常通过乙醇胺和氯乙酸反应制得。反应可在常温下进行，生成氨基乙酸和氯化氢，后者可通过进一步处理得到氯化物和水。
安全信息：
氨基乙酸为刺激性物质，请避免直接接触皮肤和眼睛，使用时应佩戴防护手套和护目镜。
避免吸入其蒸气，应保持通风良好的工作环境。
如不慎摄入或发生吸入过量，应立即寻求医疗救助。
在储存和使用过程中，应远离高温和明火，避免与强氧化剂接触。
使用前请详细阅读并遵守产品的安全操作指南和相关法规。
最后更新：2024-04-09 02:00:09
供应商列表
胶糖的上游原料
胶糖的下游产品
您刚刚浏览过
你知道吗？
微信搜索化工百科或扫描下方二维码，添加化工百科小程序，随时随地查信息！