胸腺嘧啶
胸腺嘧啶(Thymine)
CAS: 65-71-4
化学式: C5H6N2O2
| 中文名 | 胸腺嘧啶 |
| 英文名 | Thymine |
| 别名 | 胸腺素 胸腺激素 胸腺嘧啶 胸腺间氮苯 5-甲基尿嘧啶 5-甲基脲嘧啶 2,4-二羟基-5-甲基嘧啶 胸腺嘧啶,2,4-二羟基(酮基)-5-甲基嘧啶 |
| 英文别名 | Thy THYMIN Thymine THYMINE 5-Methyluracil 5-methyl-uracil 5-methyl uracil thymin(purinebase) LABOTEST-BB LT00848102 5-methylpyrimidine-2,4-diol 5-Methyl-2,4-dioxypyrimidine 5-Methylpyrimidine-2,4-dione 2,4-dioxy-5-methyl pyrimidine 2,4-Dihydroxy-5-methylpyrimidine 5-Methyl-2,4(1H,3H)-pyrimidinedione 5-methylpyrimidine-2,4(1H,3H)-dione 4(1H,3H)-Pyrimidinedione,5-methyl-2 2,4(1H,3H)-Pyrimidinedione, 5-methyl- Thymine 2-4-Dihydroxy-5-methylpyrimidine |
| CAS | 65-71-4 |
| EINECS | 200-616-1 |
| 化学式 | C5H6N2O2 |
| 分子量 | 126.11 |
| InChI | InChI=1/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9) |
| InChIKey | RWQNBRDOKXIBIV-UHFFFAOYSA-N |
| 密度 | 1.3541 (rough estimate) |
| 熔点 | ~320 °C (dec.) (lit.) |
| 沸点 | 234.21°C (rough estimate) |
| 闪点 | 198°C |
| 水溶性 | Soluble in hot water. Slightly soluble in alcohol. |
| 蒸汽压 | 4.25E-07mmHg at 25°C |
| 溶解度 | DMSO (微溶)，甲醇 (微溶，加热) |
| 折射率 | 1.5090 (estimate) |
| 酸度系数 | 9.94(at 25℃) |
| 存储条件 | Sealed in dry,Room Temperature |
| 稳定性 | 稳定。与强氧化剂不相容。 |
| 敏感性 | Sensitive to light |
| 外观 | 粉末 |
| 颜色 | White |
| Merck | 14,9398 |
| BRN | 607626 |
| 物化性质 | 白色结晶粉末，常温难溶于水，微溶于醇，溶于碱液、酸、甲酰胺，DMF及吡啶。熔点320-330℃。 |
| MDL号 | MFCD00006026 |
| 危险品标志 | Xi - 刺激性物品 |
| 风险术语 | R36 - 刺激眼睛。 R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
| 安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 S37/39 - 戴适当的手套和护目镜或面具。 S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 |
| WGK Germany | 2 |
| RTECS | XP2100000 |
| TSCA | Yes |
| 海关编号 | 29335990 |
| 上游原料 | 醋酸 甲醇 甲基丙烯酸甲酯 乙醇 |
| 下游产品 | 齐多夫定 |
| 参考资料 展开查看 | 1. 王慧敏, 冯雪松. 应用氧化石墨烯/阳离子纤维素复合物的毛细管电泳分离研究[J]. 分析试验室, 2015, 34(012):1395-1398. 2. 张磊, 王燕华, 刘畅,等. 驴皮胶及鹿皮胶的化学品质分析与评价[J]. 食品科学, 2018, 039(022):57-63. 3. 冯卫生, 李方, 郭孟焕,等. 怀山药中的一个新吡嗪衍生物[J]. 药学学报, 2017(08):101-103. 4. 高坤 宫瑞泽 李珊珊 等. UPLC法同时测定人参中13种核苷类成分[J]. 食品工业 2019. 5. 代莉莉, 金珊霞, 范梦莹,等. 季铵化β-环糊精接枝壳聚糖涂层用于毛细管电泳分离的研究[J]. 分析试验室, 2017, 08(v.36):15-18. 6. Ma, Ke, et al. "A sensitive and selective “turn-on” fluorescent probe for Hg 2+ based on thymine–Hg 2+–thymine complex with an aggregation-induced emission feature." Analytical Methods 6.7 (2014): 2338-2342. 7. Zhen Yang, Mingji Li, Hongji Li, Huayi Li, Cuiping Li, Baohe Yang, Polycrystalline boron-doped diamond-based electrochemical biosensor for simultaneous detection of dopamine and melatonin, Analytica Chimica Acta, Volume 1135, 2020, Pages 73-82, ISSN 0003-2 8. Huang, Dihui, et al. "Determination of global DNA methylation level by capillary electrophoresis using octyl-modified quaternized cellulose as an electrolyte additive." Analytical and bioanalytical chemistry 406.12 (2014): 2771-2777.https://doi.org/10.1007 9. Song, G., Zhang, R., Jiang, X. et al. Nitrogen-doped reduced graphene oxide as a sensing platform for detection of guanine and application in cell necrosis. Chem. Pap. 74, 89–98 (2020). https://doi.org/10.1007/s11696-019-00856-0 10. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera 11. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang,An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera 12. [IF=6.558] Zhen Yang et al."Polycrystalline boron-doped diamond-based electrochemical biosensor for simultaneous detection of dopamine and melatonin."Anal Chim Acta. 2020 Oct;1135:73 13. [IF=4.464] Junqing Qin et al."Growth of monolayer and multilayer graphene on glassy carbon electrode for simultaneous determination of guanine, adenine, thymine, and cytosine."J Electroanal Chem. 2021 Aug;895:115403 14. [IF=3.935] Hengqiang Zhao et al."An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicerae Japonicae."J Pharmaceut Biomed. 2019 Oct;175:112758 15. [IF=6.558] Tianrun Zhang et al."Molecularly imprinted Ni-polyacrylamide-based electrochemical sensor for the simultaneous detection of dopamine and adenine."Anal Chim Acta. 2022 Apr;1202:339689 16. [IF=6.529] Yarigui Bao et al."Therapeutic effects of Chinese medicine Di-Long (Pheretima vulgaris) on rheumatoid arthritis through inhibiting NF-κB activation and regulating Th1/Th2 balance."Biomed Pharmacother. 2022 Mar;147:112643 |
胸腺嘧啶 - 介绍
易溶于碱液并成盐，溶于酸、甲酰胺，DMF及吡啶。溶于热水，微溶于冷水、乙醇、乙醚。335～337℃分解。
最后更新：2022-10-16 17:27:44
供应商列表
现货供应
产品名: 司他夫定杂质1 (司他夫定EP杂质A) 去供应商网站查看 询盘CAS: 65-71-4
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
电话: 0714-3999186
手机: 15671228036
电子邮件: 2853786052@qq.com
QQ: 2853786052
微信: 15671228036
产品描述: 25431S
现货供应
产品名: 司他夫定杂质1 (司他夫定EP杂质A) 去供应商网站查看 询盘CAS: 65-71-4
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
电话: 0714-3999186
手机: 15671228036
电子邮件: 2853786052@qq.com
QQ: 2853786052
微信: 15671228036
产品描述: 25431S
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