血管紧缩素II_化工百科

中文名	血管紧张素II醋酸盐
英文名	Angiotensin II human acetate
别名	血管紧缩素II 血管緊縮素 II 人血管紧缩素II 血管紧张素II醋酸盐血管紧张素 II 醋酸盐血管紧张素II X醋酸盐人血管紧缩素II(-20℃) ANGIOTENSIN II HUMAN 乙酸盐
英文别名	HYPERTENSIN II ANGIOTENSIN II ACETATE SALT ANGIOTENSIN II ACETATE HUMAN Angiotensin II human acetate ANGIOTENSIN II, HUMAN, SYNTHETIC ANGIOTENSIN II HUMAN ACETATE SALT ANGIOTENSIN II, MASS SPEC STANDARD ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT
CAS	68521-88-0
EINECS	206-182-3
化学式	C52H75N13O14
分子量	1106.25
溶解度	水: 25毫克/毫升，澄清，无色
存储条件	−20°C
外观	粉末
颜色	orange
体外研究	Most of the known actions of Angiotensin II (Ang II) are mediated by AT 1 receptors, the AT 2 receptor contributes to the regulation of blood pressure and renal function. Angiotensin II raises blood pressure (BP) by a number of actions, the most important ones being vasoconstriction, sympathetic nervous stimulation, increased aldosterone biosynthesis and renal actions. Other Angiotensin II actions include induction of growth, cell migration, and mitosis of vascular smooth muscle cells, increased synthesis of collagen type I and III in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. These actions are mediated by type 1 Ang II receptors (AT 1 ). At the cellular level, responsiveness to Angiotensin II is conferred by the expression of the two classes of angiotensin receptors (AT 1 and AT 2 ). The effects of Angiotensin II to increase blood pressure are mediated by AT1 receptors.
体内研究	To distinguish the AT 1 receptor population that is critical for the pathogenesis of hypertension, osmotic minipumps are implanted s.c. into each animal to infuse Angiotensin II (1,000 ng/kg/min) continuously for 4 weeks. Angiotensin II causes hypertension by activating AT 1 receptors in the kidney promoting sodium reabsorption.
WGK Germany	3
FLUKA BRAND F CODES	3-10

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CAS: 68521-88-0
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产品名: 血管紧张素 II 醋酸盐去供应商网站查看询盘
CAS: 68521-88-0
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产品描述: 中文名：血管紧张素 II 醋酸盐英文名:Angiotensin II human acetate CAS:68521-88-0 规格:99% 产地:中国上海

上海麦克林生化科技股份有限公司

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产品名: 血管紧张素II醋酸盐去供应商网站查看询盘
CAS: 68521-88-0
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