中文名 | 4,6-二氨基-5-甲酰胺基嘧啶 |
英文名 | 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE |
别名 | 腺苷杂质33 4,6-二氨基-5-甲酰胺基嘧啶 4,6-二氨基-5-甲酰基氨基嘧啶 4,6-二氨基-5-甲酰胺基嘧啶盐酸盐 4,6-二氨基-5-甲酰基氨基嘧啶盐酸盐 N-(4,6-DIAMINOPYRIMIDIN-5-YL)甲酰胺 |
英文别名 | FAPy-adenine DIAMINO-15N2) FAPYADENINE(FORMYL-13C 4,6-diamino-5-n-formamidopyrimidine 4,6-DIAMONO-5-(FORMYLAMINO)PYRIMIDNE 4,6-DIAMINO-5-(FORMYLAMINO)-PYRIMIDINE 4,6-Diamino-5-(Formylamino)-Pyrimidine HCl 4,6-Diaminobenzene-5-formamidopyrimide-formyl-13C, diamino-15N2 |
CAS | 5122-36-1 |
EINECS | 200-258-5 |
化学式 | C5H7N5O |
分子量 | 153.14 |
存储条件 | −20°C |
体外研究 | In the absence of the external field the FAPy-adenine is able to form pairs with all four canonical nucleic acid bases. In contrast, in the presence of the external field the mispairing abilities of FAPy-adenine become insignificant since the most stable dimers are formed with thymine. |
体内研究 | The nuclear DNA damage by oxygen-derived radicals is increased in Alzheimer's disease and support the concept that the brain is under increased oxidative stress in Alzheimer's disease. |
WGK Germany | 3 |
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