斜方半面形结晶。对石蕊显酸性。不溶于甲醇、乙醇、乙醚苯,溶于酸、碱。
天冬氨酸经乙酰化制得。
生化试剂。
中文名 | L-天冬素 |
英文名 | L-Asparagine |
别名 | 门冬酰胺 天门冬酰胺 L-天冬素 L-天冬碱 L-天冬酰胺 L-酰胺天冬酸 L-天门冬酰胺 L-天冬酰胺酸 L-天冬酰氨,无水 L-天门冬酰胺无水物 L-(+)-天冬酰胺酸 L-2-氨基琥珀酸酰胺 L-天冬酰胺(无水物) L-(+)-有水天冬酰胺酸 L-(+)-无水天冬酰胺酸 L-天门冬酰胺, 2-氨基-3-氨基甲酰丙酸 |
英文别名 | ASN H-ASN-OH H-Asn-OH ASPARAGINE Asparagine L-Asparagine L-ASPARAGINE ASPARTIC ACID L-(+)-ASPARAGINE ASPARAGINIC ACID (S)-(+)-ASPARAGINE L-ASPARTIC ACID 4-AMIDE L-2-Aminosuccinamic acid L-2-AMINOSUCCINAMIC ACID L-2-AMINOBUTANEDIOIC ACID (S)-(+)-2-Aminosuccinamic acid 4-AMIDE-2-aminosuccinamic acid 2-amino-3-carbamoylpropanoic acid (2S)-2-amino-3-(aminomethoxy)propanoic acid (S)-2-AMINOSUCCINIC ACID 4-AMIDEl-aspargine |
CAS | 70-47-3 |
EINECS | 200-735-9 |
化学式 | C4H8N2O3 |
分子量 | 132.12 |
InChI | InChI=1/C4H10N2O3/c5-2-9-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8)/t3-/m0/s1 |
密度 | 1,543g/cm |
熔点 | 235 °C (dec.) (lit.) |
沸点 | 244.01°C (rough estimate) |
比旋光度 | 34.5 º (c=10, 2N HCl) |
闪点 | 147.7°C |
水溶性 | H2O: 20 g/L (20 oC) , clear, colorless |
蒸汽压 | 6.51E-05mmHg at 25°C |
溶解度 | 几乎不溶于甲醇,乙醇,乙醚,苯。溶于酸和碱。 |
折射率 | 1.4880 (estimate) |
酸度系数 | 2.17(at 20℃) |
存储条件 | Keep in dark place,Inert atmosphere,Room temperature |
稳定性 | 稳定,但可能对湿度敏感。与强氧化剂不相容。 |
敏感性 | Hygroscopic |
外观 | 粉末 |
颜色 | White |
气味 | sltly sweet taste |
Merck | 14,837 |
BRN | 1723527 |
物化性质 | 白色斜方晶系晶体或结晶性粉末。稍有甜味。熔点约234℃。重结晶方法以水最佳,其次是乙醇。遇碱水解成天冬氨酸。加热其水溶液亦分解。溶于水(3g/100L,25℃),几乎不溶于乙醇和乙醚。水溶液呈酸性。非必需氨基酸。如缺乏则影响发育,能调节脑及神经细胞的代谢功能。天然品存在于各种豆类等中。 |
MDL号 | MFCD00064401 |
危险品标志 | Xn - 有害物品 |
风险术语 | R20/21/22 - 吸入、皮肤接触及吞食有害。 R36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
安全术语 | S24/25 - 避免与皮肤和眼睛接触。 S36 - 穿戴适当的防护服。 S26 - 不慎与眼睛接触后,请立即用大量清水冲洗并征求医生意见。 |
危险品运输编号 | UN 2811 6.1 / PGIII |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10 |
TSCA | Y |
海关编号 | 29241900 |
Hazard Class | IRRITANT |
上游原料 | 氢氧化铵 硅藻土 L-苯丙酰胺 |
下游产品 | 阿维菌素 D-天冬酰胺 D-果糖 门冬氨酸鸟氨酸杂质 N'-(三苯甲基)-L-天冬酰胺 |
参考资料 展开查看 | 1. 吴飞, 刘梦迪, 李月侠,等. 天冬中总氨基酸及多糖的提取工艺研究[J]. 池州学院学报, 2017, 031(003):60-63. 2. 李晓娇 何忠梅 郑京玉 等. GC-MS、RP-HPLC法测定奇亚籽中脂溶性成分及氨基酸含量[J]. 食品研究与开发 2017(16):162-166. 3. 伍淑婕 龚积霞 聂辉 等. 九头狮子草提取物在模型体系中对丙烯酰胺的抑制作用研究[J]. 食品科技 2019 v.44;No.335(09):262-269. 4. 王婷婷,郜玉钢,臧埔,赵岩,何忠梅,祝洪艳,张连学.复方麦鹿芪人参制剂主要成分变化及其在肝癌H22荷瘤小鼠体内的抗肿瘤作用[J].吉林大学学报(医学版),2017,43(04):698-704+858-859. 5. 马长中, 罗章, 辜雪冬. 林芝砖红绒盖牛肝菌的营养成分分析及评价[J]. 食品科学, 2016, 37(024):124-129. 6. 陈思, 郜玉钢, 臧埔,等. 鹿角脱盘及其5种提取部位21种氨基酸含量对比分析[J]. 药物分析杂志, 2017(10):1851-1857. 7. 祝洪艳, 张荻, 张力娜,等. 柱前衍生化HPLC法检测紫苏子和紫苏叶中氨基酸的含量[J]. 药物分析杂志, 2017(10):1858-1864. 8. Li An, Yongliang Yuan, Jingwei Ma, Hong Wang, Xiuying Piao, Junfeng Ma, Junfeng Zhang, Ling Zhou, Xujin Wu, NMR-based metabolomics approach to investigate the distribution characteristics of metabolites in Dioscorea opposita Thunb. cv. Tiegun, Food Chemist 9. Weifeng Chen, Guo Lv, Xiang Liu, Jiaying Yan, Qichun Zhang, Dong-Sheng Li,A universal high-efficient and reusable “on–off” switch for the on-demand hydrogen evolution,Chemical Engineering Journal Advances,Volume 7,2021,100128,ISSN 2666-8211,https:// 10. [IF=5.923] Cuihua Chen et al."Variations in Physiology and Multiple Bioactive Constituents under Salt Stress Provide Insight into the Quality Evaluation of Apocyni Veneti Folium."Int J Mol Sci. 2018 Oct;19(10):3042 11. [IF=4.411] Cuihua Chen et al."Quality Evaluation of Apocyni Veneti Folium from Different Habitats and Commercial Herbs Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Multivariate Statistical Analysis."Molecules. 2018 Mar;23(3):5 12. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254 13. [IF=2.896] Jing Ke et al."Development of a gradient micellar liquid chromatographic method eluting from micellar mode to high submicellar mode for the rapid separation of free amino acids."Anal Methods-Uk. 2017 Mar;9(11):1762-1770 14. [IF=1.913] Xie Yunfei et al."Rapid Determination of Amino Acids in Beer, Red Wine, and Donkey-Hide Gelatin by Gradient Elution of HPLC: From Micellar Liquid Chromatography to High Submicellar Liquid Chromatography."J Aoac Int. 2018 Jan;101(1):249-255 15. [IF=7.514] Li An et al."NMR-based metabolomics approach to investigate the distribution characteristics of metabolites in Dioscorea opposita Thunb. cv. Tiegun."Food Chem. 2019 Nov;298:125063 16. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4 17. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697 18. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC–MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243 19. [IF=2.097] Ke Jing et al."Isocratic micellar liquid chromatography using mixed anionic and non-ionic surfactants as mobile phase additives for separation of 17 free amino acids."Chem Pap. 2019 Oct;73(10):2417-2426 20. [IF=3.463] Xiaomei Dai et al."S-alk(en)ylcysteine sulfoxides biosynthesis and free amino acids profile in different parts of postharvest chive (Allium schoenoprasum L.)."SCIENTIA HORTICULTURAE. 2022 Sep;303:111191 |
斜方半面形结晶。对石蕊显酸性。不溶于甲醇、乙醇、乙醚苯,溶于酸、碱。
天冬氨酸经乙酰化制得。
生化试剂。
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