中文名 | SH5-07 |
英文名 | SH5-07 |
别名 | 化合物SH5-07 STAT3抑制剂(SH5-07) 4-(N-(4--环己基苄基)-2-(2,3,4,5,6-五氟-N-甲基苯磺胺基)乙酰胺基)-N-羟基苯甲酰胺 |
英文别名 | SH5-07 SH5-07 (SH-5-07) Benzamide, 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-N-hydroxy- |
CAS | 1456632-41-9 |
化学式 | C29H28F5N3O5S |
分子量 | 625.61 |
密度 | 1.437±0.06 g/cm3(Predicted) |
溶解度 | 溶于DMSO |
酸度系数 | 9.03±0.10(Predicted) |
存储条件 | -20℃ |
参考资料 展开查看 | 1: Lopez-Tapia F, Brotherton-Pleiss C, Yue P, Murakami H, Costa Araujo AC, Reis Dos Santos B, Ichinotsubo E, Rabkin A, Shah R, Lantz M, Chen S, Tius MA, Turkson J. Linker Variation and Structure-Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors. ACS Med Chem Lett. 2018 Feb 16;9(3):250-255. doi: 10.1021/acsmedchemlett.7b00544. eCollection 2018 Mar 8. PubMed PMID: 29541369; PubMed Central PMCID: PMC5846032. 2: Yue P, Lopez-Tapia F, Paladino D, Li Y, Chen CH, Namanja AT, Hilliard T, Chen Y, Tius MA, Turkson J. Hydroxamic Acid and Benzoic Acid-Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In Vitro and In Vivo. Cancer Res. 2016 Feb 1;76(3):652-63. doi: 10.1158/0008-5472.CAN-14-3558. Epub 2015 Jun 18. PubMed PMID: 26088127; PubMed Central PMCID: PMC4684502. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 1.598 ml | 7.992 ml | 15.984 ml |
5 mM | 0.32 ml | 1.598 ml | 3.197 ml |
10 mM | 0.16 ml | 0.799 ml | 1.598 ml |
5 mM | 0.032 ml | 0.16 ml | 0.32 ml |
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