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中文名 | Quarfloxin (CX-3543) |
英文名 | Quarfloxin (CX-3543) |
别名 | |
CAS | 865311-47-3 |
EINECS | |
化学式 | C35H33FN6O3 |
分子量 | 604.67 |
inchi | |
包装信息 | 5 mg |
价格 | $298 |
产品描述 | Quarfloxin (CX-3543) Quarfloxin, also known as Quarfloxacin and CX-3543, is a fluoroquinolone derivative with antineoplastic activity. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells. Disruption of this G-quadruplex DNA:protein interaction in aberrant rRNA biogenesis may result in the inhibition of ribosome synthesis and tumor cell apoptosis. |
产品链接 | https://www.bocsci.com/quarfloxin-cas-865311-47-3-item-84-153274.html |
更新日期 | 2025-04-30 11:27:47 |