Name | Dihydroxyacetone |
Synonyms | Dihyxal Chromelin Ketochromin Dihydroxyacetone Aliphatic ketone 1,3-Dihydroxyacetone 1,3-Dihydroxypropanone PROPANE-1,3-DIOL-2-ONE 1,3-dihydroxy-2-propanon 1,3-Dihydroxy-2-propanone 1,3-dihydroxypropan-2-one 1,3-Dihydroxydimethyl ketone |
CAS | 96-26-4 |
EINECS | 202-494-5 |
InChI | InChI=1/C3H6O3/c4-1-3(6)2-5/h4-5H,1-2H2 |
Molecular Formula | C3H6O3 |
Molar Mass | 90.08 |
Density | 1.1385 (rough estimate) |
Melting Point | 75-80 °C |
Boling Point | 107.25°C (rough estimate) |
Flash Point | 97.3°C |
JECFA Number | 1716 |
Water Solubility | >250 g/L (20 ºC) |
Vapor Presure | 0.002-0.33Pa at 20-50℃ |
Appearance | powder |
Color | White |
pKa | 12.45±0.10(Predicted) |
Storage Condition | Store at +2°C to +8°C. |
Stability | Stable. Combustible. Hygroscopic. |
Refractive Index | 1.4540 (estimate) |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29141900 |
Toxicity | CHROMELIN ? DIHYDROXYACETONE ? 1,3DIHYDROXYACETONE ? 1,3-DIHYDROXYPROPANONE ? DIHYXAL ? NSC-24343 ? OTAN ? OXATONE ? SOLEAL ? 2PROPANONE, 1,3-DIHYDROXY- ? TRIULOSE ? VITICOLOR |
Reference Show more | 1. [IF=7.053] Y.T. Xu et al."Ultraefficient stabilization of high internal phase emulsions by globular proteins in the presence of polyols: Importance of a core-shell nanostructure."Food Hydrocolloid. 2020 Oct;107:105968 |
FEMA | 4033 | DIHYDROXYACETONE |
LogP | -1.95 at 20℃ |
surface tension | 68.85mN/m at 1g/L and 20 ℃ |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Overview | dihydroxyacetone is a naturally occurring ketose that is biodegradable, edible and non-toxic to the human body and the environment, is a multi-functional additives, can be used in cosmetics, medicine and food industry. |
dihydroxyacetone | the chemical name of dihydroxyacetone (DHA) is 1, 3-dihydroxy-2-propanone, is a commonly used ingredients in cosmetics, with skin moisturizing, imitation Sun (self-tanning) and hair dyeing function. Currently, DHA does not fall within the regulatory scope of European Union Cosmetic Regulation (EC) No. 1223/2009. In 2008, the Scientific Committee on Consumer Safety (SCCS) of the European Union received a set of applications from companies to support the Safety of DHA as a cosmetic ingredient. The research data show that the concentration of not more than 10% of DHA as a sunscreen in the use of cosmetics is safe. In addition, DHA at a concentration of not more than 14% is safe for use in spray cosmetics as a sunscreen. In May, 2019, SCCS received another application to evaluate the safety of DHA with a concentration of not more than 6.25% as a hair dye in resident (non-oxidative) hair dye cosmetics. According to the drug dynamics, skin irritation and sensitization, acute toxicity, reproductive toxicity, mutagenic, carcinogenic and other safety evaluation data provided by the enterprise, the European Union consumer safety Scientific Committee (SCCS) after the evaluation, it was concluded that DHA at a concentration of not more than 6.25% is safe for use as a hair coloring ingredient in resident (non-oxidative) hair coloring cosmetics. Resident (non-oxidative) hair coloring cosmetics with a DHA concentration of not more than 6.25% as a hair coloring ingredient are considered safe when used in combination with tanning milk or creams with a DHA concentration of not more than 10%. |
trait | white powder with sweet taste of 1, 3-dihydroxyacetone, |
Application | 1, 3-dihydroxyacetone can be applied in the following fields: 1. Dihydroxyacetone used in cosmetics industry is mainly used as a raw material for cosmetics, especially as a sunscreen has a special effect, can prevent excessive evaporation of skin moisture, moisture, sunscreen and UV radiation. In addition, the ketone functional group in DHA can react with the amino acid and amino group of skin keratin to form a Brown polymer, so that people's skin produces an artificial brown, so it can also be used as a simulated agent for Sun skin color, A brown or tan skin that looks the same as that obtained with prolonged exposure to sunlight is obtained, making it look beautiful. 2. Increase the lean meat rate of pigs. Dihydroxyacetone is an intermediate product of sugar metabolism, which plays an important role in the process of sugar metabolism, and has the function of reducing |
Use | pharmaceutical intermediates, chemical raw materials and food additives. As a pharmaceutical intermediate, Dihydroxyacetone can synthesize some drugs for treating cardiovascular diseases. Dihydroxyacetone can be used in cosmetics to prevent excessive evaporation of skin moisture, and has a moisturizing and sunscreen effect on the skin, UV radiation protection |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |