Name | 2,3,4-Trifluoronitrobenzene |
Synonyms | 4-chloro-2-fluroaniline 3,4,5 TRIFLUORONITROBENZEN 2,3,4-Dichloronitrobenzene 2,3,4-Trifluornitrobenzene 2,3,4-Trifluoronitrobenzene 2,3,4-TRIFLUORONITROBRNZENE 2,3,4-trifluoro nitrobenzene 1,2,3-Trifluoro-4-nitrobenzene 1-nitro-2,3,4-trifluorobenzene 2,3,4-TRIFLUORONITROBENZENEOFLOXACIN |
CAS | 771-69-7 |
EINECS | 212-238-4 |
InChI | InChI=1/C7H2Cl2F4/c8-4-1-3(7(11,12)13)2-5(9)6(4)10/h1-2H |
Molecular Formula | C6H2F3NO2 |
Molar Mass | 177.08 |
Density | 1.541 g/mL at 25 °C (lit.) |
Boling Point | 92 °C/20 mmHg (lit.) |
Flash Point | 200°F |
Vapor Presure | 2.4mmHg at 25°C |
Appearance | clear liquid |
Specific Gravity | 1.541 |
Color | Light yellow to Yellow to Orange |
BRN | 2449746 |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.492(lit.) |
Physical and Chemical Properties | trait light yellow liquid. |
Use | It is used as an intermediate of ofloxacin, lomefloxacin and norfloxacin |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes. |
UN IDs | UN2810 |
WGK Germany | 3 |
HS Code | 29042090 |
Hazard Note | Irritant |
Hazard Class | 6.1 |
Packing Group | III |
Raw Materials | 2,5-Dichloroaniline 2,6-Dichloroaniline Sulfanilamide Potassium fluoride Fluoroboric acid Nitric acid Hydrochloric acid |
Downstream Products | Lomefloxacin hydrochloride |
light yellow oily liquid. The boiling point is 92 ℃(2. 7kPa,20mmHg), the relative density is 1.541, the refractive index is 1. 4920, and the flash point is 93 ℃. This product is irritating.
2, 6-chloroaniline was prepared by Schiemann reaction, nitration and fluorination.
This product is mainly used for the synthesis of a new generation of fluoroquinolone antibacterial agent, ofloxacin. It can also be used for the synthesis of quinonic acid antibacterial drug lomefloxacin and the like.
The packaging is lined with plastic iron drum, 50kg/barrel.
Use | used as intermediate of ofloxacin, lomefloxacin and norfloxacin used as drug, this product is mainly used for the synthesis of a new generation of fluoroquinolone antibacterial agent, ofloxacin. It can also be used for the synthesis of quinonic acid antibacterial drug lomefloxacin and the like. |
production method | with 2, 6-dichloroaniline as raw material, it is prepared by Schiemann reaction, nitration and fluorination. |