2-(4-cyanophenyl)-2,2-difluoroacetic acid - Names and Identifiers
2-(4-cyanophenyl)-2,2-difluoroacetic acid - Physico-chemical Properties
Molecular Formula | C9H5F2NO2
|
Molar Mass | 197.1383064 |
Storage Condition | Room Temprature |
2-(4-cyanophenyl)-2,2-difluoroacetic acid - Upstream Downstream Industry
2-(4-cyanophenyl)-2,2-difluoroacetic acid - Introduction
2-(4-cyanophenyl)-2,2-difluoroacetic acid is an organic compound with the chemical formula C9H5F2NO2. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow crystalline or powder
-Melting Point: about 83-87 ℃
-Solubility: Soluble in most organic solvents such as alcohols, ethers and chlorinated hydrocarbons
-Stability: relatively stable at room temperature, but decomposed by heat, it will hydrolyze when exposed to water
Use:
-Material synthesis: 2-(4-cyanophenyl)-2,2-difluoroacetic acid can be used as an important starting material in organic synthesis, and can be used to synthesize other organic compounds, such as pesticides, drugs and dyes.
-Chemical research: Due to its unique structure and properties, it is also widely used in the field of chemical research, such as organic synthesis and catalytic reactions.
Method:
The preparation method of 2-(4-cyanophenyl)-2,2-difluoroacetic acid can be carried out by the following reaction steps:
1. Benzoxonitrile (4-cyanophenol) is reacted with dichloroacetic anhydride to generate 2-(4-cyanophenyl)-2,2-dichloroacetic acid.
2.2-(4-cyanophenyl)-2,2-dichloroacetic acid is then reacted with hydrogen difluoride under basic conditions to form 2-(4-cyanophenyl)-2,2-difluoroacetic acid.
Safety Information:
2-(4-cyanophenyl)-2,2-difluoroacetic acid is relatively stable under correct use, but the following safety precautions still need to be paid attention:
-Because it may cause irritation to the skin, eyes and respiratory tract, personal protective equipment such as chemical safety masks, protective gloves and goggles should be worn during operation.
-Avoid inhaling gas or solution vapor, and maintain a well-ventilated working environment.
-Avoid contact with strong oxidants and combustibles to reduce the risk of fire and explosion.
-Observe proper chemical management regulations during handling and storage to ensure safe use.
Before using 2-(4-cyanophenyl)-2,2-difluoroacetic acid, please carefully read and understand the relevant safety data sheets and instructions, and strictly follow the laboratory safety procedures.
Last Update:2024-04-09 21:04:16