4-(3-TERT-BUTYL-1,2,4-OXADIAZOL-5-YL)PHENYLBORONIC ACID - Names and Identifiers
4-(3-TERT-BUTYL-1,2,4-OXADIAZOL-5-YL)PHENYLBORONIC ACID - Physico-chemical Properties
4-(3-TERT-BUTYL-1,2,4-OXADIAZOL-5-YL)PHENYLBORONIC ACID - Introduction
4-(3-TERT-BUTYL-1, 2,4-oxadiazol-5-yl) PHENYLBORONIC ACID is an organic compound with the chemical formula C15H19BN2O3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Melting Point: about 110-115 ℃
-Molecular weight: 282.14g/mol
Use:
4-(3-TERT-BUTYL-1, 2,4-oxadiazol-5-yl) PHENYLBORONIC ACID is a reagent commonly used in organic synthesis and is commonly used in the synthesis of catalysts, ligands and functional molecules. It can participate in Suzuki-Miyaura coupling reaction, C- H activation reaction and other organic synthesis reaction.
Method:
The preparation of 4-(3-TERT-BUTYL-1, 2,4-oxadiazol-5-yl) PHENYLBORONIC ACID can be carried out by the following steps:
1. Reaction of tert-butyl copper bromide with 3-tert-butyl-1, 2,4-Oxadiazole in a solvent gives copper 3-tert-butyl-1, 2,4-Oxadiazole.
2. The reaction of copper 3-TERT-BUTYL-1,2,4-Oxadiazole with PHENYLBORONIC ACID in the presence of an oxidizing agent gives 4-(3-TERT-BUTYL-1, 2,4-oxadiazol-5-yl) PHENYLBORONIC ACID.
Safety Information:
- 4-(3-TERT-BUTYL-1, 2,4-oxadiazol-5-yl) PHENYLBORONIC ACID has certain irritation and should avoid direct contact with skin and eyes.
-During use, you should wear appropriate protective equipment, such as lab gloves and goggles.
-During storage, it should be stored in a sealed container, away from fire and oxidizing agents.
-Before use, you should carefully read and follow the relevant safety operating guidelines and instructions.
Last Update：2024-04-10 22:29:15