4-Nitrophenylboronic acid pinacol ester
(4-Nitrophenyl)boronic acid, pinacol ester
CAS: 171364-83-3
Molecular Formula: C12H16BNO4
4-Nitrophenylboronic acid pinacol ester - Names and Identifiers
4-Nitrophenylboronic acid pinacol ester - Physico-chemical Properties
| Molecular Formula | C12H16BNO4 |
| Molar Mass | 249.07 |
| Density | 1.14±0.1 g/cm3(Predicted) |
| Melting Point | 112-116 °C (lit.) |
| Boling Point | 357.5±25.0 °C(Predicted) |
| Flash Point | 170°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 5.58E-05mmHg at 25°C |
| Appearance | powder or crystals |
| Color | White to Orange to Green |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.515 |
4-Nitrophenylboronic acid pinacol ester - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 2 |
| HS Code | 29333990 |
| Hazard Note | Harmful/Store Cold |
| Hazard Class | IRRITANT |
4-Nitrophenylboronic acid pinacol ester - Introduction
(4-Nitrophenyl)boronic acid, pinacol ester is an organic compound with the chemical formula C6H5B(NO2)2OCH2CH2OH. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow liquid
-Density: 1.38g/cm³
-Boiling point: 220-225 ° C
-Melting point:-10 ° C
-Solubility: Soluble in organic solvents such as ether, chloroform and acetone.
Use:
- (4-Nitrophenyl)boronic acid, pinacol ester is an important organic synthesis intermediate, often used in the preparation of other compounds.
-It can be used as a component of high energy density materials, such as fuel additives and propellants in explosives.
-It can also be used as a chemical reagent in the fields of dyes and fluorescent probes.
Method:
(4-Nitrophenyl)boronic acid, pinacol ester can be prepared by Nitro reaction. The specific steps are as follows:
1. The p-nitrobenzene borate and Hydroxyethyl alcohol are reacted and heated under alkaline conditions.
2. After the reaction, the product is obtained by cooling crystallization.
Safety Information:
- (4-Nitrophenyl)boronic acid, pinacol ester has high explosion sensitivity. Please strictly control the fire source and electrostatic discharge to avoid potentially dangerous conditions such as impact or friction.
-It should be stored in a dark, dry and well-ventilated place, away from combustibles and oxidants.
-Wear appropriate personal protective equipment such as goggles, gloves and laboratory clothing during operation.
-For the use and handling of this compound, please refer to the relevant safety guidelines and regulations, and carry out correct disposal or storage.
Nature:
-Appearance: Colorless to light yellow liquid
-Density: 1.38g/cm³
-Boiling point: 220-225 ° C
-Melting point:-10 ° C
-Solubility: Soluble in organic solvents such as ether, chloroform and acetone.
Use:
- (4-Nitrophenyl)boronic acid, pinacol ester is an important organic synthesis intermediate, often used in the preparation of other compounds.
-It can be used as a component of high energy density materials, such as fuel additives and propellants in explosives.
-It can also be used as a chemical reagent in the fields of dyes and fluorescent probes.
Method:
(4-Nitrophenyl)boronic acid, pinacol ester can be prepared by Nitro reaction. The specific steps are as follows:
1. The p-nitrobenzene borate and Hydroxyethyl alcohol are reacted and heated under alkaline conditions.
2. After the reaction, the product is obtained by cooling crystallization.
Safety Information:
- (4-Nitrophenyl)boronic acid, pinacol ester has high explosion sensitivity. Please strictly control the fire source and electrostatic discharge to avoid potentially dangerous conditions such as impact or friction.
-It should be stored in a dark, dry and well-ventilated place, away from combustibles and oxidants.
-Wear appropriate personal protective equipment such as goggles, gloves and laboratory clothing during operation.
-For the use and handling of this compound, please refer to the relevant safety guidelines and regulations, and carry out correct disposal or storage.
Last Update：2024-04-10 22:29:15
