Cyclopropylacetyl chloride
Cyclopropylacetyl chloride
CAS: 54322-65-5
Molecular Formula: C5H7ClO
Cyclopropylacetyl chloride - Names and Identifiers
| Name | Cyclopropylacetyl chloride |
| Synonyms | Cyclopropylacetyl chloride Cyclopropaneacetyl chloride cyclopropylacetic acid chloride |
| CAS | 54322-65-5 |
Cyclopropylacetyl chloride - Physico-chemical Properties
| Molecular Formula | C5H7ClO |
| Molar Mass | 118.56 |
| Density | 1.193±0.06 g/cm3(Predicted) |
| Boling Point | 135.8±9.0 °C(Predicted) |
| Storage Condition | -20℃ |
| Sensitive | Irritant, Stench |
| MDL | MFCD11110393 |
Cyclopropylacetyl chloride - Introduction
Cyclopropylacetyl chloride is an organic compound with the molecular formula C5H7ClO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
Cyclopropylacetyl chloride is a colorless to yellow liquid with a pungent odor. It is insoluble in water but miscible with organic solvents such as ethanol and ether. Its boiling point is about 105-107 degrees Celsius and its density is about 1.119 g/mL.
Use:
Cyclopropylacetyl chloride is widely used in organic synthesis. It is an important reagent that can be used in the preparation of other compounds, such as acid chlorides, acyl amines, ketones, etc. These derivatives are commonly used in the synthesis of drugs, dyes and pesticides.
Method:
The preparation of Cyclopropylacetyl chloride is generally obtained by reacting cyclopropylacetic acid with thionyl chloride (SOCl2). The specific step is that cyclopropylacetic acid and thionyl chloride are heated to react under appropriate temperature conditions to generate Cyclopropylacetyl chloride and sodium bisulfate, and the reaction product usually needs to go through appropriate purification steps.
Safety Information:
Cyclopropylacetyl chloride is an organic chloride and should be handled with care. During use, contact with the skin and inhalation of its vapors should be avoided. Wear personal protective equipment such as goggles, gloves and lab coats when using. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help. From a safety point of view, it should be handled in a well-ventilated laboratory, and the compound should be stored and handled properly.
Nature:
Cyclopropylacetyl chloride is a colorless to yellow liquid with a pungent odor. It is insoluble in water but miscible with organic solvents such as ethanol and ether. Its boiling point is about 105-107 degrees Celsius and its density is about 1.119 g/mL.
Use:
Cyclopropylacetyl chloride is widely used in organic synthesis. It is an important reagent that can be used in the preparation of other compounds, such as acid chlorides, acyl amines, ketones, etc. These derivatives are commonly used in the synthesis of drugs, dyes and pesticides.
Method:
The preparation of Cyclopropylacetyl chloride is generally obtained by reacting cyclopropylacetic acid with thionyl chloride (SOCl2). The specific step is that cyclopropylacetic acid and thionyl chloride are heated to react under appropriate temperature conditions to generate Cyclopropylacetyl chloride and sodium bisulfate, and the reaction product usually needs to go through appropriate purification steps.
Safety Information:
Cyclopropylacetyl chloride is an organic chloride and should be handled with care. During use, contact with the skin and inhalation of its vapors should be avoided. Wear personal protective equipment such as goggles, gloves and lab coats when using. In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical help. From a safety point of view, it should be handled in a well-ventilated laboratory, and the compound should be stored and handled properly.
Last Update：2024-04-09 15:18:02
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