(2-Bromoethyl)benzene
(2-Bromoethyl)benzene
CAS: 103-63-9
Molecular Formula: C8H9Br
(2-Bromoethyl)benzene - Names and Identifiers
| Name | (2-Bromoethyl)benzene |
| Synonyms | PHENETHYL BROMIDE Phenethyl bromide 2-phenethylbromide 2-Phenethyl bromide 2-Bromoethyl-benzene β-Bromoethyl benzene PHENYL ETHYL BROMIDE (2-Bromoethyl)benzene 2-Phenylethyl bromide (2-bromoethyl)-benzen 1-BROMO-2-PHENYLETHANE 2-Phenyl-1-bromoethane beta-Bromophenylethane .beta.-Phenylethylbromide |
| CAS | 103-63-9 |
| EINECS | 203-130-8 |
| InChI | InChI=1/C8H9Br/c9-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2 |
| InChIKey | WMPPDTMATNBGJN-UHFFFAOYSA-N |
(2-Bromoethyl)benzene - Physico-chemical Properties
| Molecular Formula | C8H9Br |
| Molar Mass | 185.06 |
| Density | 1.355g/mLat 25°C(lit.) |
| Melting Point | -56 °C |
| Boling Point | 220-221°C(lit.) |
| Flash Point | 193°F |
| Water Solubility | INSOLUBLE |
| Solubility | 0.039g/l |
| Vapor Presure | 0.167mmHg at 25°C |
| Appearance | Liquid |
| Color | Clear colorless to pale yellow |
| BRN | 507487 |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | n20/D 1.556(lit.) |
| Physical and Chemical Properties | Boiling Point: 217-221 ℃ flash point: 89 ℃ relative density: 1.359-1.370 refractive index (n20D):1.556-1.558 |
| Use | For pharmaceutical and pesticide intermediates |
(2-Bromoethyl)benzene - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S39 - Wear eye / face protection. |
| UN IDs | UN 1993 / PGIII |
| WGK Germany | 3 |
| RTECS | CY9032000 |
| TSCA | Yes |
| HS Code | 29036990 |
(2-Bromoethyl)benzene - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | β-bromostyrene is an important intermediate for the synthesis of high efficient brominated flame retardant polybrominated styrene, it is also commonly used in the preparation of intermediates in organic synthesis. For example, β-bromophenylethane can be used to prepare the intermediate 4-(4-phenylbutoxy) benzoic acid in the preparation of pranlukast. as an anti-asthma drug, pranlukast was first developed by the Japanese Little Wild Company and was marketed in Japan in 1995. In 1999, it was found to treat allergic rhinitis. Pranlukast is a leukotriene C4/D4 receptor antagonist (lTRAs) with extremely low toxicity. It can selectively inhibit the activity of airway smooth muscle leukotriene polypeptides and has little effect on arachidonic acid metabolism enzymes, at the same time, it has no antagonistic effect on acetylcholine and serotonin, and has significant inhibition on lTC4, lTD4, lTE4 and so on. |
| Use | organic synthesis, pesticide intermediates. used as pharmaceutical and pesticide intermediates |
| production method | is derived from the reaction of phenylethyl alcohol with hydrogen bromide. Phenyl ethanol was heated to 110 ° C., hydrogen bromide was slowly introduced, and the reaction was refluxed. After completion of the reaction, the reaction mixture was cooled and washed with water, 10% sodium carbonate solution and water in this order. After drying with anhydrous potassium carbonate and fractional distillation under reduced pressure, the 97-99 ° C. (2.0kPa) fraction was collected, and the yield was more than 90%. |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:52:54
Supplier List
Featured ProductsSpot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Wechat: A2020071098
Spot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Fentanyl Impurity 12 (Fentanyl EP Impurity L) Visit Supplier Webpage Request for quotationCAS: 103-63-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: β-Bromoethylbenzene Request for quotationCAS: 103-63-9
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Product Name: (2-Bromoethyl)benzene Request for quotation
CAS: 103-63-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 103-63-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: 2-Phenyl Ethyl Bromide Request for quotation
CAS: 103-63-9
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
CAS: 103-63-9
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
Featured ProductsSpot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: 15335994747
Email: 3521670276@qq.com
Mobile: 15335994747
QQ: 3521670276
Wechat: A2020071098
Spot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: (2-Bromoethyl)benzene Request for quotationCAS: 103-63-9
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: Fentanyl Impurity 12 (Fentanyl EP Impurity L) Visit Supplier Webpage Request for quotationCAS: 103-63-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: β-Bromoethylbenzene Request for quotationCAS: 103-63-9
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Wechat: +86 19849939632
Product Name: (2-Bromoethyl)benzene Request for quotation
CAS: 103-63-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 103-63-9
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Product Name: 2-Phenyl Ethyl Bromide Request for quotation
CAS: 103-63-9
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
CAS: 103-63-9
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
QQ: 472954302
Product List: View Catalog
View History