(2-Chlorophenyl)methanesulfonyl chloride

(2-Chlorophenyl)methanesulfonyl chloride - Names and Identifiers

Name	(2-Chlorophenyl)methanesulfonyl chloride
Synonyms	S45 S26 S30 2-Chlorobenzylsulfonyl chloride 2-Chloro-alpha-toluenesulfonyl chloride (2-Chlorophenyl)methanesulfonyl chloride Benzenemethanesulfonyl chloride, 2-chloro- (2-CHLORO-PHENYL)-METHANESULFONYL CHLORIDE (2-Chlorophenyl)methanesulfonyl chloride, 2-Chloro-α-toluenesulfonyl chloride, 2-Chlorobenzenemethanesulfonyl chloride
CAS	77421-13-7
InChI	InChI=1/C7H6Cl2O2S/c8-7-4-2-1-3-6(7)5-12(9,10)11/h1-4H,5H2

(2-Chlorophenyl)methanesulfonyl chloride - Physico-chemical Properties

Molecular Formula	C7H6Cl2O2S
Molar Mass	225.09
Density	1.499g/cm³
Melting Point	59-63 °C
Boling Point	321.2°C at 760 mmHg
Flash Point	148°C
Vapor Presure	0.000569mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.578

(2-Chlorophenyl)methanesulfonyl chloride - Risk and Safety

Risk Codes	R34 - Causes burns R29 - Contact with water liberates toxic gas R14 - Reacts violently with water R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	3261
WGK Germany	3
Hazard Class	IRRITANT

(2-Chlorophenyl)methanesulfonyl chloride - Introduction

(2-Chlorophenyl)methanesulfonyl chloride is a colorless to yellowish liquid with a chemical formula of C7H6ClClOS and a molecular weight of 226.54g/mol. It has a pungent odor and can be decomposed or volatilized.

(2-Chlorophenyl)methanesulfonyl chloride has a wide range of applications in organic synthesis. It is commonly used as an acylation reagent, can react with alcohol, phenol, amine and other compounds to generate the corresponding methyl sulfonyl compound. The compound can be used as an intermediate for the preparation of drugs, pesticides, dyes and polymer materials.

A method for preparing (2-Chlorophenyl)methanesulfonyl chloride is obtained by reacting benzylsulfonyl chloride with ferrous chloride. First, benzylsulfonyl chloride is reacted with ferrous chloride in an appropriate solvent, and the reaction temperature is usually carried out at room temperature. After completion of the reaction, the product is extracted and purified by distillation or other methods.

(2-Chlorophenyl)methanesulfonyl chloride is an irritating and corrosive compound that is irritating to the skin, eyes and respiratory tract. Wear protective gloves, goggles and respiratory protection during operation. Avoid contact with skin, eyes and taking. When stored, it should be stored in a sealed container, away from fire and oxidizing agents. Because it is easy to decompose or volatilize, it needs to be kept closed to avoid light and high temperature.

Last Update：2024-04-09 21:04:16