(2s)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoic acid
(S)-N-BOC-Propargylglycine
CAS: 63039-48-5
Molecular Formula: C10H15NO4
(2s)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoic acid - Names and Identifiers
| Name | (S)-N-BOC-Propargylglycine |
| Synonyms | Boc-Pra-OH RARECHEM BK PT 0256 Boc-Gly(propargyl)-OH BOC-L-PROPARGYLGLYCINE Boc-L-Propargylglycine (S)-N-BOC-PROPARGYLGLYCINE Boc-(S)-2-Propargylglycine (S)-N-BOC-Propargylglycine (S)-N-Boc-propargylglycine(e.e.) L-TERT-BUTOXYCARBONYL-L-PROPARGYL GLYCINE (S)-N-(TERT-BUTOXYCARBONYL)-PROPARGYLGLYCINE (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoate (S)-N-TERT-BUTOXYCARBONYL-2-AMINO-4-PENTYNOIC ACID (S)-N-tert-Butoxycarbonyl-2-amino-4-pentynoic acid (2S)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoic acid |
| CAS | 63039-48-5 |
| InChI | InChI=1/C10H15NO4/c1-5-6-7(8(12)13)11-9(14)15-10(2,3)4/h1,7H,6H2,2-4H3,(H,11,14)(H,12,13)/p-1/t7-/m0/s1 |
| InChIKey | AMKHAJIFPHJYMH-ZETCQYMHSA-N |
(2s)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoic acid - Physico-chemical Properties
| Molecular Formula | C10H15NO4 |
| Molar Mass | 213.23 |
| Density | 1.2177 (rough estimate) |
| Melting Point | 85.5 °C |
| Boling Point | 353.22°C (rough estimate) |
| Flash Point | 174.7°C |
| Water Solubility | Soluble in water. |
| Vapor Presure | 2.49E-06mmHg at 25°C |
| Appearance | Crystalline Powder |
| Color | Off-white to light yellow |
| BRN | 5739897 |
| pKa | 3.53±0.10(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.4368 (estimate) |
| MDL | MFCD01320855 |
(2s)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29241990 |
| Hazard Class | IRRITANT |
(2s)-2-[(tert-butoxycarbonyl)amino]pent-4-ynoic acid - Introduction
(S)-N-BOC-Propargylglycine ((S)-N-BOC-Propargylglycine) is an organic compound consisting of (S)-propynylglycine and an imide (BOC) group.
The properties of this compound include: colorless solid, soluble in some organic solvents such as dimethyl sulfoxide and dichloromethane, and insoluble in water. Its chemical structure contains the backbone structure of propargyl (propargyl) functional groups and amino acids.
(S)-N-BOC-Propargylglycine are mainly used for catalytic reactions in organic synthesis and the construction of chiral molecules. Specific applications include:
1. As a substrate in the cross-coupling reaction of carbon-carbon bonds, it is used to construct C- C bonds and C- N bonds;
2. as amino acid derivatives for the synthesis of drugs and bioactive molecules.
Preparation of (S)-N-BOC-Propargylglycine mainly by the following steps:
1. Condensation reaction of (S)-propynylglycine and imide (BOC) to obtain (S)-N-BOC-Propargylglycine.
Regarding the safety information of the compound,(S)-N-BOC-Propargylglycine is a chemical agent and needs to be handled with caution. The following are some general safety considerations:
1. Avoid contact with skin, eyes and respiratory tract. Use personal protective equipment such as chemical protective gloves, protective glasses and protective masks.
2. Keep away from open flames and high temperatures during operation to avoid harmful gases.
3. When storing, place the (S)-N-BOC-Propargylglycine in a closed container and store it in a dry and cool place.
However, for specific safety information and operating instructions, please refer to the specific safety data sheet (MSDS) of the compound and the safety instructions provided by the supplier.
The properties of this compound include: colorless solid, soluble in some organic solvents such as dimethyl sulfoxide and dichloromethane, and insoluble in water. Its chemical structure contains the backbone structure of propargyl (propargyl) functional groups and amino acids.
(S)-N-BOC-Propargylglycine are mainly used for catalytic reactions in organic synthesis and the construction of chiral molecules. Specific applications include:
1. As a substrate in the cross-coupling reaction of carbon-carbon bonds, it is used to construct C- C bonds and C- N bonds;
2. as amino acid derivatives for the synthesis of drugs and bioactive molecules.
Preparation of (S)-N-BOC-Propargylglycine mainly by the following steps:
1. Condensation reaction of (S)-propynylglycine and imide (BOC) to obtain (S)-N-BOC-Propargylglycine.
Regarding the safety information of the compound,(S)-N-BOC-Propargylglycine is a chemical agent and needs to be handled with caution. The following are some general safety considerations:
1. Avoid contact with skin, eyes and respiratory tract. Use personal protective equipment such as chemical protective gloves, protective glasses and protective masks.
2. Keep away from open flames and high temperatures during operation to avoid harmful gases.
3. When storing, place the (S)-N-BOC-Propargylglycine in a closed container and store it in a dry and cool place.
However, for specific safety information and operating instructions, please refer to the specific safety data sheet (MSDS) of the compound and the safety instructions provided by the supplier.
Last Update：2024-04-09 21:54:55
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