(3-methylphenyl)methanesulfonyl chloride - Names and Identifiers
(3-methylphenyl)methanesulfonyl chloride - Physico-chemical Properties
Molecular Formula | C8H9ClO2S
|
Molar Mass | 204.67 |
Density | 1.325g/cm3 |
Melting Point | 48 °C |
Boling Point | 304.5°C at 760 mmHg |
Flash Point | 138°C |
Vapor Presure | 0.00156mmHg at 25°C |
Storage Condition | Room Temprature |
Sensitive | Irritant |
Refractive Index | 1.556 |
MDL | MFCD04117457 |
(3-methylphenyl)methanesulfonyl chloride - Risk and Safety
(3-methylphenyl)methanesulfonyl chloride - Introduction
(3-methylphenyl)methanesulfonyl chloride, also known as (3-methylphenyl) sulfonyl chloride, is an organic compound. It has a chemical formula of C8H9ClO2S and a molecular weight of 200.68g/mol. The following is a description of the nature, use, preparation and safety information of (3-methylphenyl)methanesulfonyl chloride:
Nature:
-Appearance: Colorless to light yellow liquid.
-Solubility: Soluble in many organic solvents, such as dimethyl sulfoxide, ethanol, etc.
-Melting point: about 15-18 ℃.
-Boiling point: about 231-234 ℃.
-Density: Approximately 1.26 g/mL.
Use:
- (3-methylphenyl)methanesulfonyl chloride is a common reagent in chemical synthesis, used to synthesize tolylmethanesulfonyl amino acid derivatives.
-It can also be used to synthesize active ingredients of drugs, such as anti-inflammatory drugs, anti-cancer drugs, etc.
-In organic synthesis, it is often used as a sulfonyl chloride reagent.
Preparation Method:
(3-methylphenyl) The preparation of methanesulfonyl chloride is generally obtained by reacting 3-methylbenzoic acid with sulfonyl chloride. The reaction conditions are generally in an anhydrous organic solvent, such as dimethyl sulfoxide or methylene chloride.
Safety Information:
- (3-methylphenyl)methanesulfonyl chloride is irritating to the skin, eyes and respiratory tract, and direct contact should be avoided when using.
-During use and storage, a well-ventilated environment should be maintained to avoid toxic gases.
-It belongs to a class of chemicals in organic synthesis and should be properly stored and kept away from fire and oxidants.
-Wear appropriate personal protective equipment such as protective gloves, goggles and masks during use.
-It should not be discharged into water sources or the environment, and should comply with relevant environmental regulations.
Last Update:2024-04-09 02:00:46