Name | (4-Pyridyl)acetone |
Synonyms | Einecs 228-605-7 4-Pyridyl acetone (4-Pyridyl)acetone 4-Pyridinolacetone 1-(4-Pyridyl)acetone 1-pyridin-4-ylacetone (4-PYRIDINEYL)-ACETONE 1-(4-Pyridyl)-2-acetone 1-(4-Pyridyl)-2-propanone 1-(pyridin-4-yl)propan-2-one |
CAS | 6304-16-1 |
EINECS | 228-605-7 |
InChI | InChI=1/C8H9NO/c1-7(10)6-8-2-4-9-5-3-8/h2-5H,6H2,1H3 |
InChIKey | ILRVKOYYFFNXDB-UHFFFAOYSA-N |
Molecular Formula | C8H9NO |
Molar Mass | 135.16 |
Density | 1.046±0.06 g/cm3(Predicted) |
Melting Point | 13°C |
Boling Point | 143°C 20mm |
Flash Point | 143°C/20mm |
Water Solubility | Slightly soluble in water. |
Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
Vapor Presure | 0.059mmHg at 25°C |
Appearance | Oil |
Color | Light Brown to Brown |
BRN | 110960 |
pKa | 4.90±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.5225 |
MDL | MFCD00129043 |
Physical and Chemical Properties | Liquid. Boiling point 130-132 °c/1.5kPa. |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37 - Wear suitable gloves. |
HS Code | 29337900 |
Introduction | 1-(4-pyridyl) acetone is yellow liquid, it is a key intermediate in the synthesis of the cardiotonic drug milrinone. |
Use | an intermediate for the cardiotonic drug milrinone. pharmaceutical intermediates, mainly used in the synthesis of milrinone |
production method | 1-(4-pyridyl) acetone can be used with 4-methyl pyridine and phenyl lithium, ethyl acetate was obtained by reaction. |