(S)-(-)-1-(1-Naphthyl)ethylamine
(S)-(-)-1-(1-Naphthyl)ethylamine
CAS: 10420-89-0
Molecular Formula: C12 H13 N
(S)-(-)-1-(1-Naphthyl)ethylamine - Names and Identifiers
| Name | (S)-(-)-1-(1-Naphthyl)ethylamine |
| Synonyms | L-A-(1-NAPHTHYL)ETHYLAMINE (S)-1-(1-NAPHTHYL)ETHYLAMINE (1S)-1-(1-Naphthyl)ethanamine (1R)-1-naphthalen-1-ylethanamine (S)-(-)-1-(1-Naphthyl)ethylamine (1S)-1-NAPHTHALEN-1-YLETHANAMINE (S)-1-(NAPHTHALEN-1-YL)ETHANAMINE (1S)-1-naphthalen-1-ylethanaminium L-ALPHA-(ALPHA-NAPHTHYL)ETHYLAMINE (S)(-)-ALPHA-(1-NAPHTHYL)ETHYLAMINE (-)-1-[(S)-1-Aminoethyl]naphthalene (S)-α-Methylnaphthalene-1-methanamine (αS)-α-Methylnaphthalene-1-methanamine (S)-(-)-ALPHA-(1-AMINOETHYL)NAPHTHALENE [S,(-)]-α-Methyl-1-naphthalenemethanamine |
| CAS | 10420-89-0 |
| EINECS | 600-536-0 |
| InChI | InChI=1/C12H13N/c1-9(13)11-8-4-6-10-5-2-3-7-12(10)11/h2-9H,13H2,1H3/p+1/t9-/m0/s1 |
| InChIKey | RTCUCQWIICFPOD-VIFPVBQESA-N |
(S)-(-)-1-(1-Naphthyl)ethylamine - Physico-chemical Properties
| Molecular Formula | C12 H13 N |
| Molar Mass | 171.24 |
| Density | 1.067 g/mL at 20 °C (lit.) |
| Boling Point | 153 °C/11 mmHg (lit.) |
| Specific Rotation(α) | -60 º (C=2, MEOH) |
| Flash Point | >230°F |
| Solubility | Soluble in chloroform, ethanol. |
| Vapor Presure | 0.00214mmHg at 25°C |
| Appearance | Liquid |
| Color | brown |
| BRN | 2208024 |
| pKa | 9.26±0.40(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.623(lit.) |
| Physical and Chemical Properties | Storage Conditions: 2-8℃ sensitivity: Air Sensitive WGK Germany:3 RTECS:QJ6963000 |
(S)-(-)-1-(1-Naphthyl)ethylamine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | 2735 |
| WGK Germany | 3 |
| RTECS | QJ6963000 |
| FLUKA BRAND F CODES | 10-34 |
| TSCA | Yes |
| HS Code | 29214990 |
| Hazard Note | Irritant |
| Hazard Class | 8 |
| Packing Group | II |
(S)-(-)-1-(1-Naphthyl)ethylamine - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | 1-(1-naphthyl) ethylamine has two configurations, namely (S)-(-)-1-(1-naphthyl) ethylamine and (R)-1-(1-naphthyl) ethylamine, wherein (S)-(-)-1-(1-naphthyl) ethylamine is an efficient resolving agent for resolving acetylated amino acid derivatives, and (R)-1-(1-naphthyl) ethylamine can not only be used as a resolving agent, but also an important pharmaceutical intermediate. |
| synthesis method | (S)-(-)-1-(1-naphthyl) one of the synthetic methods of ethylamine-biological resolution method: the enzyme, especially Candida antarctica lipase B (CALB) as the catalyst, the use of different chiral 1-(1-naphthyl) the transesterification rate of ethylamine was different, (R)-1-(1-naphthyl) ethylamine was esterified, while (S)-(-)-1-(1-naphthyl) ethylamine was retained, and then the compounds with different chirality were obtained. |
| Use | intermediate of cinacalcet hydrochloride |
Last Update：2024-04-09 19:05:07
Supplier List
Spot supply
Product Name: (S)-(-)-1-(1-Naphthyl)ethylamine Request for quotationCAS: 10420-89-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: (S)-(-)-1-(1-Naphthyl)ethylamine Request for quotationCAS: 10420-89-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: (S)-(-)-1-(1-Naphthyl)ethylamine Request for quotationCAS: 10420-89-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: (S)-(-)-1-(1-Naphthyl)ethylamine Request for quotationCAS: 10420-89-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
View History