à-(benzenesulfonyl)acetophenone

à-(benzenesulfonyl)acetophenone - Names and Identifiers

Name	1-phenyl-2-(phenylsulphonyl)ethan-1-one
Synonyms	TIMTEC-BB SBB009912 2-BENZENESULFONYLACETOPHENONE 2-(PHENYLSULFONYL)ACETOPHENONE à-(benzenesulfonyl)acetophenone ALPHA-(PHENYLSULFONYL)ACETOPHENONE 1-phenyl-2-(phenylsulfonyl)ethanone ALPHA-(PHENYLSULPHONYL)ACETOPHENONE 2-(benzenesulfonyl)-1-phenylethan-1-one 1-phenyl-2-(phenylsulphonyl)ethan-1-one 1-Phenyl-2-(phenylsulphonyl)ethan-1-one
CAS	3406-03-9
EINECS	222-292-0
InChI	InChI=1/C14H12O3S/c15-14(12-7-3-1-4-8-12)11-18(16,17)13-9-5-2-6-10-13/h1-10H,11H2

à-(benzenesulfonyl)acetophenone - Physico-chemical Properties

Molecular Formula	C14H12O3S
Molar Mass	260.31
Density	1.2959 (rough estimate)
Melting Point	93-95°C(lit.)
Boling Point	373.57°C (rough estimate)
Flash Point	305°C
Solubility	soluble in Benzene
Vapor Presure	4.43E-09mmHg at 25°C
Appearance	powder to crystal
Color	White to Orange to Green
BRN	1879574
Storage Condition	Room Temprature
Refractive Index	1.5050 (estimate)
MDL	MFCD00025043

à-(benzenesulfonyl)acetophenone - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29309090
Hazard Class	IRRITANT

à-(benzenesulfonyl)acetophenone - Introduction

1-phenyl-2-(phenylsulphonyl)ethan-1-one is an organic compound with the chemical formula C14H12O2S. The following is a description of its nature, use, preparation and safety information:

Nature:
1-phenyl-2-(phenylsulphonyl)ethan-1-one is a white crystalline solid with an intense aroma. It is almost insoluble in water at room temperature, but can be dissolved in many organic solvents, such as ethanol, methanol and dichloromethane.

Use:
1-phenyl-2-(phenylsulphonyl)ethan-1-one has certain biological activity and is widely used in the field of drug synthesis and organic synthesis. It can be used as an important intermediate and play a key role in the synthesis of various organic compounds. In addition, it can also be used as an ingredient in flavors and monosodium glutamate.

Preparation Method:
1-phenyl-2-(phenylsulphonyl)ethan-1-one can be obtained by reacting acetophenone with benzenesulfonyl chloride under alkaline conditions. The specific preparation method includes adding acetophenone and benzenesulfonyl chloride in ethanol in the presence of potassium acetate and stirring the reaction at room temperature.

Safety Information:
The use and handling of 1-phenyl-2-(phenylsulphonyl)ethan-1-one should pay attention to the following safety precautions:
1. use should wear protective glasses and gloves, avoid direct contact with the skin and eyes.
2. in the use and storage process should pay attention to prevent fire and electrostatic spark.
3. avoid inhaling the dust or vapor of the solution, and operate in a well-ventilated place when using it.
4. storage should be away from oxidants and fire, keep the container sealed, stored in a cool, dry place.
5. If there is any discomfort or accident during use, stop using it immediately and seek medical help.

Last Update：2024-04-09 20:52:54