二邻甲苯基磷酰乙酸乙酯

二邻甲苯基磷酰乙酸乙酯 - Names and Identifiers

Name	Ditolylphosphonoaceticacidethylester
Synonyms	ETHYL DI-O-TOLYLPHOSPHONOACETATE Ditolylphosphonoaceticacidethylester DI-O-TOLYLPHOSPHONOACETIC ACID ETHYL ESTER Di-o-tolylphosphonoacetic acid ethyl ester ethyl [bis(2-methylphenoxy)phosphoryl]acetate Ethyl Di-o-tolylphosphonoacetate [Horner-Emmons Reagent] Acetic acid, 2-[bis(2-methylphenoxy)phosphinyl]-, ethyl ester
CAS	188945-41-7
InChI	InChI=1/C18H21O5P/c1-4-21-18(19)13-24(20,22-16-11-7-5-9-14(16)2)23-17-12-8-6-10-15(17)3/h5-12H,4,13H2,1-3H3

二邻甲苯基磷酰乙酸乙酯 - Physico-chemical Properties

Molecular Formula	C18H21O5P
Molar Mass	348.33
Density	1.19
Boling Point	240 °C / 3mmHg
Flash Point	241.623°C
Vapor Presure	0mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Yellow to Orange
Storage Condition	Room Temprature
Refractive Index	1.5330-1.5350
MDL	MFCD01321166

二邻甲苯基磷酰乙酸乙酯 - Introduction

Pb, also known as LEPA, is an organophosphorus compound. It has the following properties and uses:

Nature:
-Appearance: colorless transparent liquid.
-Solubility: Soluble in organic solvents, such as ethanol and dimethylformamide.
-Stability: Stable at room temperature, but may decompose under high temperature or light.
-Combustibility: flammable, may burn in case of open flame or high temperature.

Use:
- LEPA can be used as a catalyst in organic synthesis, especially with good catalytic activity in carbonylation reactions.
-It can also be used to synthesize aluminum phosphate resin, and is widely used in surface coating, plastics and adhesives.

Method: The preparation of
is usually carried out through a three-step reaction:
1. Toluene reacts with phosphorous chloride to obtain Chlorinated Diphenyl phosphorus (DPP-Cl).
2. DPP-Cl reacts with sodium hydroxide to obtain diphenyl phosphate (DPPO).
3. Finally, DPPO is reacted with ethoxyacetic acid to form fluorene (LEPA).

Safety Information:
- LEPA is an organic phosphorus compound that may cause harm to the human body. Exposure to or inhalation of LEPA may cause irritation, allergy, or toxic symptoms.
-It is a flammable substance, avoid contact with fire sources.
-Use good ventilation and wear appropriate protective equipment, such as gloves and goggles.
-Be careful when storing and handling LEPA, and follow chemical safety procedures.

Last Update：2024-04-09 21:00:56