偶氮丝胺酸
AZASERINE
CAS: 115-02-6
Molecular Formula: C5H7N3O4
偶氮丝胺酸 - Names and Identifiers
| Name | AZASERINE |
| Synonyms | azs cl337 ci337 ci-337 azaserin AZASERINE cn-15,757 O-DIAZOACETYL-L-SERINE serine,diazoacetate(ester) |
| CAS | 115-02-6 |
| EINECS | 204-061-6 |
偶氮丝胺酸 - Physico-chemical Properties
| Molecular Formula | C5H7N3O4 |
| Molar Mass | 173.13 |
| Density | 1.5830 (rough estimate) |
| Melting Point | 146-162° (dec) |
| Boling Point | 303.75°C (rough estimate) |
| Specific Rotation(α) | D27.5 -0.5° (c = 8.46% in H2O at pH 5.18) |
| Solubility | H2O: 50mg/mL, clear, yellow |
| Appearance | lyophilized powder |
| Color | Light-yellow needles from EtOH (aq) |
| Merck | 13,902 |
| BRN | 1726602 |
| pKa | 8.55(at 25℃) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6190 (estimate) |
偶氮丝胺酸 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3462 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | VT9625000 |
| FLUKA BRAND F CODES | 10 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 in mice, rats (mg/kg/day): 150, 170 orally (Sternberg, Philips) |
偶氮丝胺酸 - Reference
| Reference Show more | 1. [IF=3.682] Wenhui Xu et al."Effect of Dihydroartemisinin on Plasmodium NADH-Dependent Glutamate Synthase: The Implication in Malaria Management."Am J Chinese Med. 2019 Sep;47(06):1325-1343 |
偶氮丝胺酸 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 5.776 ml | 28.881 ml | 57.761 ml |
| 5 mM | 1.155 ml | 5.776 ml | 11.552 ml |
| 10 mM | 0.578 ml | 2.888 ml | 5.776 ml |
| 5 mM | 0.116 ml | 0.578 ml | 1.155 ml |
Last Update：2024-01-02 23:10:35
偶氮丝胺酸 - Reference Information
| (IARC) carcinogen classification | 2B (Vol. 10, Sup 7) 1987 |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | azazoline (CI-337) is a competitive glutamine amide transferase inhibitor. |
| category | toxic substances |
| toxicity grade | high toxicity |
| Acute toxicity | oral-rat LD50: 170 mg/kg; Oral-mouse LD50: 150 mg/kg |
| flammability hazard characteristics | flammability; Toxic NOx smoke from combustion |
| storage and transportation characteristics | ventilation and low temperature drying; Separate storage |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, water mist |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 21:11:58
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Multiple SpecificationsSpot supply
Product Name: CI-337; O-Diazoacetyl-L-serine; P-165 Visit Supplier Webpage Request for quotationCAS: 115-02-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
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Product Name: Azaserine Visit Supplier Webpage Request for quotationCAS: 115-02-6
Tel: +86-400-900-4166
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Wechat: 18621343501
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Product Name: Azaserine Visit Supplier Webpage Request for quotationCAS: 115-02-6
Tel: +86-18821248368
Email: Int06@meryer.com
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Spot supply
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View History
偶氮丝胺酸
皂黄
3-[(叔丁氧羰基)氨基]-1-(苯基甲基)-3-吡咯烷羧酸
C5/C9 copolymerized petroleum resin
SKF-385 hydrochloride
Z-PHE-ALA
DRIED BARIUM HYDROXIDE
SODIUM SEC-BUTOXIDE
5-核糖核苷酸二钠
methyl 3-hydroxy-2-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
皂黄
3-[(叔丁氧羰基)氨基]-1-(苯基甲基)-3-吡咯烷羧酸
C5/C9 copolymerized petroleum resin
SKF-385 hydrochloride
Z-PHE-ALA
DRIED BARIUM HYDROXIDE
SODIUM SEC-BUTOXIDE
5-核糖核苷酸二钠
methyl 3-hydroxy-2-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate