Name | Nefiracetam |
Synonyms | DMMPA dmppa dm9384 NEFIRACETAM Nefiracetam DM-9384 DMMPA DZL-221 [(2,6-dimethylphenyl)aminocarbonylmethyl]chloride n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid 2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide DM-9384, (2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide) |
CAS | 77191-36-7 |
EINECS | 636-080-4 |
InChI | InChI=1/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17) |
InChIKey | NGHTXZCKLWZPGK-UHFFFAOYSA-N |
Molecular Formula | C14H18N2O2 |
Molar Mass | 246.3 |
Density | 1.187±0.06 g/cm3(Predicted) |
Melting Point | 151-155°C |
Boling Point | 458.5±33.0 °C(Predicted) |
Flash Point | 231.1°C |
Solubility | Soluble in DMSO (49 mg/ml at 25 °C), water (5 mg/ml at 25 °C), and ethanol (49 mg/m |
Vapor Presure | 1.36E-08mmHg at 25°C |
Appearance | solid |
Color | white to off-white |
Merck | 14,6439 |
pKa | 13.77±0.70(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.593 |
MDL | MFCD00209882 |
Physical and Chemical Properties | Melting Point 151-155°C |
Use | Activator of L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. |
Hazard Symbols | Xn - Harmful |
Risk Codes | 22 - Harmful if swallowed |
WGK Germany | 3 |
RTECS | UX9655650 |
Toxicity | LD50 in mice (mg/kg): 421 i.v.; 1766 orally (Betzing, 1982) |