Name | Solasonine |
Synonyms | PURAPURIN NSC 82149 Solasonin PURAPURINE SOLANINE S Solasonine SOLANCARPIN SOLASODAMINE alpha-Solasonine Tomatine solaradixine Solasonine 19121-58-5 Solasoninealpha-Solasonine beta-D-Galactopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))- (9CI) |
CAS | 19121-58-5 1369-76-2 28701-66-8 77-34-9 |
EINECS | 242-826-6 |
InChI | InChI=1/C45H73NO16/c1-19-8-13-45(46-16-19)20(2)30-27(62-45)15-26-24-7-6-22-14-23(9-11-43(22,4)25(24)10-12-44(26,30)5)57-42-39(61-40-36(54)34(52)31(49)21(3)56-40)38(33(51)29(18-48)59-42)60-41-37(55)35(53)32(50)28(17-47)58-41/h6,19-21,23-42,46-55H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28-,29-,30+,31+,32-,33+,34-,35+,36-,37-,38+,39-,40+,41+,42-,43+,44+,45-/m1/s1 |
Molecular Formula | C45H73NO16 |
Molar Mass | 884.07 |
Density | 1.42 |
Melting Point | 301-303℃ |
Specific Rotation(α) | D23 -88° (c = 1.01 in pyridine); D22 -74.5° (c = 0.51 in methanol) |
Solubility | Soluble in hot ethanol and hot dioxane, slightly soluble in hot water and dilute acetic acid, insoluble in chloroform and ether. |
Appearance | It is needle crystal |
pKa | 12.78±0.70(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.627 |
MDL | MFCD00017611 |
Physical and Chemical Properties | Soluble in hot ethanol and hot dioxane, slightly soluble in hot water and dilute acetic acid, insoluble in chloroform and ether. Fruits from the Solanaceae plant Solanum aviculare Forst. |
Reference Show more | 1. Gao Jie Zhu Mingyi Huang Zuliang et al. RP-HPLC Determination of Solanine Content in Different Extracts of Solanoid Fruit [J]. 2014 20(17):46-48. 2. [IF = 4.411] Jun Yang et al."Solasonine, A Natural Glycoalkaloid Compound, Inhibits Gli-Mediated Transcriptional Activity." Molecules. 2016 Oct;21(10):1364 3. [IF = 3.266] Xun Wang et al."Solasonine inhibits glioma growth through anti-inflammatory pathways." Am J Transl Res. 2017; 9(9): 3977-3989 4. [IF = 6.244] Hong Zhang et al."Solasonine Suppresses the Proliferation of ACute Monocytic Leukemia Through the Activation of the AMPK/FOXO3A Axis." Front Oncol. 2021 Jan 29;10:614067 5. [IF = 2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis." Parasitol Res. 2021 Mar;120(3):1143-1150 |