盐酸二((S)-1-(1-萘基)乙基)胺
bis((S)-(+)-1-(1-naphthyl)ethyl)amine hydrochlori
CAS: 171867-34-8
Molecular Formula: C24H23N.ClH
盐酸二((S)-1-(1-萘基)乙基)胺 - Names and Identifiers
| Name | bis((S)-(+)-1-(1-naphthyl)ethyl)amine hydrochlori |
| Synonyms | BIS((S)-(+)-1-(1-NAPHTHYL)ETHYL)AMINE bis((S)-(+)-1-(1-naphthyl)ethyl)amine hydrochlori Bis((S)-1-(naphthalen-1-yl)ethyl)amine hydrochloride (S)-bis((S)-1-(naphthalen-1-yl)ethyl)amine hydrochloride |
| CAS | 171867-34-8 |
| EINECS | 219-511-7 |
| InChI | InChI=1/C24H23N.ClH/c1-17(21-15-7-11-19-9-3-5-13-23(19)21)25-18(2)22-16-8-12-20-10-4-6-14-24(20)22;/h3-18,25H,1-2H3;1H/t17-,18-;/m0./s1 |
盐酸二((S)-1-(1-萘基)乙基)胺 - Physico-chemical Properties
| Molecular Formula | C24H23N.ClH |
| Molar Mass | 361.91 |
| Melting Point | 280°C (dec.)(lit.) |
| Boling Point | 512.2°C at 760 mmHg |
| Flash Point | 263.5°C |
| Vapor Presure | 7.4E-11mmHg at 25°C |
盐酸二((S)-1-(1-萘基)乙基)胺 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
盐酸二((S)-1-(1-萘基)乙基)胺 - Introduction
bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride is a pharmaceutical intermediate with the following properties:
1. Appearance: A white or off-white solid.
2. Solubility: soluble in water and some organic solvents, such as alcohol and ether.
3. Melting Point: about 135-138 ° C.
4. Optical activity: It belongs to (S)-Vanderwalt isomer and has optical activity.
The main purpose of bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride:
1. Chiral drug synthesis: as a chiral ligand, it is often used as a catalytic activator, chiral inducer and important chiral intermediate in chemical synthesis.
2. Pharmaceutical field: used in the production of anticancer drugs, digestive system drugs, antidepressant drugs, etc.
Method for preparing bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride:
The usual preparation method is to react (S)-( )-(1-naphthyl) ethylamine with hydrochloric acid to generate bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride.
Safety Information:
in the operation need to pay attention to the following matters:
1. Avoid inhalation of dust and contact with skin, eyes, etc.
2. Please wear protective glasses and gloves when using.
3. Operate in a well-ventilated place to avoid prolonged exposure.
4. If accidentally ingested or inhaled, please seek medical attention.
1. Appearance: A white or off-white solid.
2. Solubility: soluble in water and some organic solvents, such as alcohol and ether.
3. Melting Point: about 135-138 ° C.
4. Optical activity: It belongs to (S)-Vanderwalt isomer and has optical activity.
The main purpose of bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride:
1. Chiral drug synthesis: as a chiral ligand, it is often used as a catalytic activator, chiral inducer and important chiral intermediate in chemical synthesis.
2. Pharmaceutical field: used in the production of anticancer drugs, digestive system drugs, antidepressant drugs, etc.
Method for preparing bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride:
The usual preparation method is to react (S)-( )-(1-naphthyl) ethylamine with hydrochloric acid to generate bis((S)-( )-1-(1-naphthyl)ethyl)amine hydrochloride.
Safety Information:
in the operation need to pay attention to the following matters:
1. Avoid inhalation of dust and contact with skin, eyes, etc.
2. Please wear protective glasses and gloves when using.
3. Operate in a well-ventilated place to avoid prolonged exposure.
4. If accidentally ingested or inhaled, please seek medical attention.
Last Update：2024-04-09 18:58:34
