(+)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole(intermidiate of Pramipexole) - Names and Identifiers
Name | (±)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole
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Synonyms | (R)-N-Despropyl PraMipexole R-2,6-Diamino-4,5,6,7-tetrahydroben-zothiazole (R)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine (+)-2,6-Diamino-4,5,6,7-Tetrahydrobenzothiazole (±)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole (R)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole (6R)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine (6R)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole (R)-4,5,6,7-Tetrahydro-Benzothiazole-2,6-Diamine (R)-4,5,6,7-TETRAHYDRO-BENZOTHIAZOLE-2,6-DIAMINE (R)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (+)-(6R)-2,6-Diamino-4,5,6,7-Tetrahydrobenzothiazole (+)-(6R)-2,6-DIAMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOLE (+)-(6R)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole (6R)-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine (+)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole(intermidiate of Pramipexole)
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CAS | 106092-11-9
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EINECS | 690-698-9 |
InChI | InChI=1/C7H11N3S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h4H,1-3,8H2,(H2,9,10)/t4-/m1/s1 |
(+)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole(intermidiate of Pramipexole) - Physico-chemical Properties
Molecular Formula | C7H11N3S
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Molar Mass | 169.25 |
Density | 1.313±0.06 g/cm3(Predicted) |
Melting Point | 228-230°C |
Boling Point | 359.0±42.0 °C(Predicted) |
Flash Point | 170.9°C |
Solubility | Methanol (Sparingly), Water (Slightly) |
Vapor Presure | 2.45E-05mmHg at 25°C |
Appearance | grayish white solid |
Color | Off-White to Pale Beige |
pKa | 9.18±0.20(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Refractive Index | 1.655 |
MDL | MFCD07369986 |
(+)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole(intermidiate of Pramipexole) - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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HS Code | 29341000 |
(+)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole(intermidiate of Pramipexole) - Introduction
()-2,6-amino -4,5,6,7-tetrahydrobenzothiazole is an organic compound with the chemical formula C7H10N2S. The following is a description of its nature, use, preparation and safety information:
Nature:
( )-2,6-amino -4,5,6,7-tetrahydrobenzothiazole is a solid, usually white crystal or powder. It is non-volatile at room temperature and has low solubility. It is a chiral compound, there is a chiral center, and there are two enantiomers.
Use:
( )-2,6-amino -4,5,6,7-tetrahydrobenzothiazole has a wide range of applications in organic synthesis. It can be used as a synthetic intermediate of chiral compounds for the preparation of drugs, pesticides and other organic compounds. In addition, it is used in the synthesis of biologically active compounds such as peptides and basic dyes.
Preparation Method:
( )-2,6-amino -4,5,6,7-tetrahydrobenzothiazole has many preparation methods, one of which is commonly used by amine and 1,2-dihalogenated aromatic hydrocarbon under alkaline conditions The condensation reaction is obtained. The specific reaction conditions can be adjusted according to the actual situation.
Safety Information:
For the safety information of ()-2,6-amino -4,5,6,7-tetrahydrobenzothiazole, the following points should be noted:
1. Because it is a chemical substance, it must follow the general safety procedures. When handling or handling this material, wear appropriate personal protective equipment, such as laboratory gloves and eye protection.
2. This compound has not been widely studied, so its long-term effects such as toxicity and carcinogenicity are not clear. Therefore, when using or handling this compound, caution should be exercised and direct contact with the skin and inhalation of its dust should be avoided.
3. Hazard assessment and safe handling are very important when handling this compound. This compound must be used and handled under the guidance of an experienced professional, following strict procedures.
Please note that this is only a basic introduction to ()-2,6-amino -4,5,6, 7-tetrahydrobenzothiazole. Specific applications and safety information may require further research and evaluation. Consult a professional or obtain more detailed and accurate information from a reliable source before using this compound.
Last Update:2024-04-09 21:04:16