(1,4'-Bipiperidine)-4'-carboxamide

(1,4'-Bipiperidine)-4'-carboxamide - Names and Identifiers

Name	(1,4'-Bipiperidine)-4'-carboxamide
Synonyms	4-piperidinoisonipecotamide 4'-carbamoyl-1,4'-bipiperidinium [1,4-Bipiperidine]-4-carboxamide 1,4'-Bipiperidinyl-4'-carboxaMide (1,4'-Bipiperidine)-4'-carboxamide (1,4'-BIPIPERIDINE)-4'-CARBOXAMIDE 4-CarbaMoyl-4-(1-piperidinyl)piperidine 4-(1-PIPERIDINO)-4-PIPERIDINECARBOXAMIDE 4-piperidin-1-ylpiperidine-4-carboxamide 4-(1-Piperidinyl)-4-(aMinocarbonyl)piperidine
CAS	39633-82-4
EINECS	254-548-2
InChI	InChI=1/C11H21N3O/c12-10(15)11(4-6-13-7-5-11)14-8-2-1-3-9-14/h13H,1-9H2,(H2,12,15)/p+2

(1,4'-Bipiperidine)-4'-carboxamide - Physico-chemical Properties

Molecular Formula	C11H21N3O
Molar Mass	211.3
Density	1.0221 (rough estimate)
Melting Point	129-132 °C
Boling Point	351°C (rough estimate)
Flash Point	188.7°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	3.06E-06mmHg at 25°C
Appearance	Solid
Color	White
pKa	16.23±0.20(Predicted)
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere
Refractive Index	1.5700 (estimate)

(1,4'-Bipiperidine)-4'-carboxamide - Risk and Safety

Risk Codes	R34 - Causes burns R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.

(1,4'-Bipiperidine)-4'-carboxamide - Introduction

(1,4 '-Bipiperidine)-4'-carboxamide is an organic compound whose chemical formula is C12H21N3O. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
(1,4 '-Bipiperidine)-4'-carboxamide is a white to pale yellow solid with a distinctive odor. Its melting point is about 169-170 degrees C, can be dissolved in some organic solvents such as ethanol and chloroform, difficult to dissolve in water.

Use:
(1,4 '-Bipiperidine)-4'-carboxamide has a wide range of applications in the field of chemistry and medicine. It can be used as an intermediate in organic synthesis for the synthesis of other compounds. In addition, it can also be used as a drug raw material and play an important role in drug research and development.

Preparation Method:
The preparation of (1,4 '-Bipiperidine)-4'-carboxamide can be based on different synthetic routes. One common method is the synthesis by N-formylation of 1,4-dipiperidine. Specifically, 1,4-dipiperidine and formyl chloride can be reacted together and then subjected to appropriate purification steps to obtain the desired product.

Safety Information:
Limited information is currently available on the toxicity and harmfulness of (1,4 '-Bipiperidine)-4'-carboxamide and related compounds. However, in general, safe practices should be followed when using or handling chemicals. It is recommended to wear appropriate protective equipment, such as gloves and safety glasses, maintain good ventilation, and avoid direct contact with the skin and inhalation of vapors generated by the compound. If you intend to use this compound, please refer to the relevant safety data sheet or consult a professional.

Last Update：2024-04-09 20:45:29