(1-(3-Fluorophenyl)cyclopentyl)methanamine

(1-(3-Fluorophenyl)cyclopentyl)methanamine - Names and Identifiers

Name	1-[1-(3-fluorophenyl)cyclopentyl]methanamine
Synonyms	(1-(3-Fluorophenyl)cyclopentyl)methanamine 1-(3-Fluorophenyl)-cyclopentaneMethanaMine 1-(3-Fluorophenyl)-cyclopentanemethanamine Cyclopentanemethanamine, 1-(3-fluorophenyl)- 1-[1-(3-fluorophenyl)cyclopentyl]methanamine Cyclopentanemethanamine, 1-(3-fluorophenyl)- (9CI)
CAS	359715-61-0
InChI	InChI=1/C12H16FN/c13-11-5-3-4-10(8-11)12(9-14)6-1-2-7-12/h3-5,8H,1-2,6-7,9,14H2

(1-(3-Fluorophenyl)cyclopentyl)methanamine - Physico-chemical Properties

Molecular Formula	C12H16FN
Molar Mass	193.26
Density	1.071g/cm³
Boling Point	281.1°C at 760 mmHg
Flash Point	134.9°C
Vapor Presure	0.00364mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.529

(1-(3-Fluorophenyl)cyclopentyl)methanamine - Introduction

1-[1-(3-fluorophenyl)cyclopentyl]methanamine is an organic compound with the chemical formula C12H16FN. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: colorless liquid or white solid
-Melting point: about 30-32 degrees Celsius
-Boiling point: about 300 degrees Celsius
-Density: about 0.98 g/ml

Use:
1-[1-(3-fluorophenyl)cyclopentyl]methanamine is frequently used as an intermediate in organic synthesis. It can be used as a raw material for the synthesis of drugs, such as antidepressants and sedative drugs.

Preparation Method:
Generally, the preparation method of 1-[1-(3-fluorophenyl)cyclopentyl]methanamine can be carried out by the following steps:
1. The reaction of cyclopentane formic acid with phenyl bromide generates cyclopentane methyl phenyl carboxylic acid.
2. Further, cyclopentane methyl phenyl carboxylic acid is reacted with stannous fluoride to obtain 1-(3-fluorophenyl) cyclopentanecarboxylic acid.
3. Finally, 1-(3-fluorophenyl) cyclopentanecarboxylic acid is reacted with ammonia to produce 1-[1-(3-fluorophenyl)cyclopentyl]methanamine.

Safety Information:
1-[1-(3-fluorophenyl)cyclopentyl]methanamine is an irritating compound that may cause irritation in contact with skin and eyes. Wear appropriate personal protective equipment, such as gloves and glasses, to avoid contact during handling.
Because it has not been extensively studied, there are limited data on its effects on the health of organisms and toxicity, so you should be careful when using and handling it, and follow relevant safety guidelines.

Last Update：2024-04-09 21:04:16