(14R)-1α-Acetoxy-7α,20-epoxy-6β,7,14-trihydroxykaur-16-en-15-one - Names and Identifiers
Name | 6,7,14-trihydroxy-15-oxo-7,20-epoxykaur-16-en-1-yl acetate
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Synonyms | Lasiodin NSC 250683 Oridonin 1-acetate 6,7,14-trihydroxy-15-oxo-7,20-epoxykaur-16-en-1-yl acetate (14R)-1α-Acetoxy-7α,20-epoxy-6β,7,14-trihydroxykaur-16-en-15-one Kaur-16-en-15-one, 1-(acetyloxy)-7,20-epoxy-6,7,14-trihydroxy-, (1α,6β,7α,14R)-
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CAS | 28957-08-6
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(14R)-1α-Acetoxy-7α,20-epoxy-6β,7,14-trihydroxykaur-16-en-15-one - Physico-chemical Properties
Molecular Formula | C22H30O7
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Molar Mass | 406.47 |
Melting Point | 238-239℃ |
Boling Point | 588℃ at 760 mmHg |
Storage Condition | 2-8℃ |
(14R)-1α-Acetoxy-7α,20-epoxy-6β,7,14-trihydroxykaur-16-en-15-one - Introduction
6,7, 14-tridroxyy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate is a natural diterpenoid with the chemical formula c₂ h₂ O. The molecular weight is 431.41g/mol. It is a yellow to yellow-green crystalline powder, soluble in organic solvents such as ethanol, ether and chloroform, and slightly soluble in water.
6,7,14-trihydroxy-15-oxo-7,20-epoxykaur-16-en-1-yl acetate has a variety of pharmacological activities and biological activities, especially has a strong inhibitory effect on anti-tumor cells. It can exert anti-tumor activity by interfering with the cell cycle and inhibiting the proliferation and metastasis of tumor cells. In addition, 6,7, 14-trihydroy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate also has anti-inflammatory, antioxidant and antibacterial activities.
6,7, 14-trihydroxyy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate is usually obtained by extracting from Castanopsis plants, such as Acer mauronis (Isodon lophanthoides) and Castanopsis mauronis (Rabdosia rubescens). The extracted 6,7, 14-trihydroxyy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate was purified by crystallization, purification and structural identification.
Regarding the safety information of 6,7, 14-trihydroxyy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate, there are not many studies reporting its toxicity and side effects. However, as a natural product, 6,7, 14-trihydroy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate is active and may have some effects on the human body. Therefore, when using 6,7, 14-trihydroy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate, it is necessary to follow appropriate laboratory practices and carry out risk assessment and safety protection measures according to the specific situation. In the application and research of 6,7, 14-trihydroy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate, it is recommended to follow the relevant regulations and guidelines. When 6,7, 14-trihydroy-15-oxo-7, 20-epoxykaur-16-en-1-yl acetate is used in clinical and medical research, more in-depth research and evaluation is needed to ensure its safety and efficacy.
Last Update:2024-04-09 21:54:55