(1R,2S)-1-Boc-2-vinylcyclopropanecarboxylic acid

(1R,2S)-1-Boc-2-vinylcyclopropanecarboxylic acid - Names and Identifiers

Name	(1R,2S)-1-(tert-Butoxycarbonylamino)-2-vinylcyclopropanecarboxylic acid
Synonyms	VINYL ACCA 1-diMethylethoxy)carbonyl]aMino]-2-ethenyl- (1R,2S)-1-Boc-2-vinylcyclopropanecarboxylic acid VINYL ACCA A.K.A (1R,2S) N-BOC-1-AMINO-2-VINYL CYC (1R,2S)-1-tert-Butoxycarbonylamino-2-vinylcyclopropanecarboxylic acid (1R,2S)-1-(tert-Butoxycarbonylamino)-2-vinylcyclopropanecarboxylic acid 1R,2S)-1-[(tert-Butoxycarbonyl)amino]-2-vinylcyclopropanecarboxylic acid (1R,2S)-N-tert-Butoxycarbonyl-1-aMino-2-vinylcyclopropanecarboxylic acid (1R,2S)-1-[(tert-butoxycarbonyl)amino]-2-ethenylcyclopropanecarboxylic acid (1R,2S)-1-[[(1,1-diMethylethoxy)carbonyl]aMino]-2-ethenyl-Cyclopropanecarboxylic acid Cyclopropanecarboxylic acid, 1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-ethenyl-, (1R,2S)-
CAS	159622-10-3 259221-77-7
EINECS	1592732-453-0
InChI	InChI=1/C11H17NO4/c1-5-7-6-11(7,8(13)14)12-9(15)16-10(2,3)4/h5,7H,1,6H2,2-4H3,(H,12,15)(H,13,14)/t7-,11?/m1/s1

(1R,2S)-1-Boc-2-vinylcyclopropanecarboxylic acid - Physico-chemical Properties

Molecular Formula	C11H17NO4
Molar Mass	227.26
Density	1.17±0.1 g/cm3(Predicted)
Boling Point	361.0±42.0 °C(Predicted)
Appearance	powder to crystal
Color	White to Light yellow to Light orange
pKa	4.95±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.508

(1R,2S)-1-Boc-2-vinylcyclopropanecarboxylic acid - Introduction

(1R,2S)-1-(tert-Butoxycarbonylamino)-acid, also known as tert-butoxycarbonylaminoacrylic acid, has the chemical formula C8H15NO3.

Nature:
(1R,2S)-1-(tert-Butoxycarbonylamino)-acrylic is a colorless liquid. It has three functional groups: tert-butoxycarbonyl (t-butoxycarbonyl,Boc), Amino, and vinyl. It is a chiral molecule, because it has two chiral centers, there are two enantiomers.

Use:
(1R,2S)-1-(tert-Butoxycarbonylamino)-acrylic acid is an important intermediate in organic synthesis. It can be used in the synthesis of other chiral compounds, such as the synthesis of chiral drugs, pesticides and natural products.

Method:
(1R,2S)-1-(tert-Butoxycarbonylamino)-The preparation of acid can be achieved by a variety of methods. A common method is to (1R,2R)-cyclopropyl glycine by HCl catalytic esterification reaction, under the appropriate temperature and reaction time, with vinyl alcohol ester exchange reaction to obtain the target product.

Safety Information:
(1R,2S)-1-(tert-Butoxycarbonylamino)-The acid is generally relatively safe under normal operating conditions. However, it is an organic compound that may be irritating to the skin, eyes and respiratory tract. Therefore, wear appropriate protective equipment such as gloves, goggles, and respiratory protection during use or operation. At the same time, the compound should be stored and handled properly to avoid contact with oxidants and combustibles, and to avoid inhalation of its vapors and dust. If necessary, it should be used in a well-ventilated place and follow relevant safety operating procedures. Before using this compound, it is best to consult its safety data sheet and operating manual to ensure safe operation.

Last Update：2024-04-09 21:11:58