(2-Fluoro-5-Methylpyridin-3-yl)boronic acid

(2-Fluoro-5-Methylpyridin-3-yl)boronic acid - Names and Identifiers

Name	2-Fluoro-5-methylpyridine-3-boronic acid
Synonyms	2-FLUORO-5-PICOLINE-3-BORONIC ACID 2-Fluoro-5-methylpyridine-3-boronicaci 2-FLUORO-5-METHYLPYRIDINE-3-BORONIC ACID 2-Fluoro-5-methylpyridine-3-boronic acid (2-Fluoro-5-Methylpyridin-3-yl)boronic acid 2-fluoro-5-methylpyridin-3-yl-3-boronic acid Boronic acid, B-(2-fluoro-5-methyl-3-pyridinyl)-
CAS	1072952-45-4

(2-Fluoro-5-Methylpyridin-3-yl)boronic acid - Physico-chemical Properties

Molecular Formula	C6H7BFNO2
Molar Mass	154.93
Storage Condition	2-8°C

(2-Fluoro-5-Methylpyridin-3-yl)boronic acid - Introduction

2-Fluoro-5-methylpyridine-3-boronic acid is an organic compound with the chemical formula C7H8BFNO. Here's a look at its nature, use, formulation and safety information.

Nature:
2-Fluoro-5-methylpyridine-3-boronic acid is a colorless crystalline solid that can be dissolved in some organic solvents such as ethers and ketones. It has good thermal stability and light stability.

Use:
2-Fluoro-5-methylpyridine-3-boronic acid is mainly used as a boron reagent in organic synthesis reactions, especially in the Suzuki reaction, as an important palladium catalyst. It can be used to construct carbon-carbon and carbon-heteroatom bonds, and synthesize various organic compounds, such as drugs, pesticides and dyes.

Preparation Method:
The preparation of 2-fluoro-5-methylpyridine-3-boronic acid can be carried out by different methods. One common method is to react 2-fluoro-5-methylpyridine with trimethylboronic acid to produce the desired product. The specific reaction conditions and operation steps need to be adjusted and optimized according to the specific experimental requirements.

Safety Information:
General laboratory safety practices should be followed in the use and handling of 2-fluoro-5-methylpyridine-3-boronic acid. It is a low-toxic compound, but care should be taken to avoid inhalation, skin contact and ingestion. Wear appropriate protective equipment such as lab gloves, goggles and lab coats during operation. Avoid contact with oxidants, strong acids and other substances. In case of accidental contact or inhalation, rinse immediately with water or seek medical attention. During storage, it should be sealed and kept in a dry, cool place, away from fire and combustibles.

Last Update：2024-04-09 02:00:41