(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid
(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid
CAS: 1217501-53-5
Molecular Formula: C11H16BNO5S
(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid - Names and Identifiers
(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid - Physico-chemical Properties
| Molecular Formula | C11H16BNO5S |
| Molar Mass | 285.12 |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD13195673 |
(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid - Introduction
(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid is an organic compound with a chemical formula of C13H19BNO5S and a molecular weight of 313.17g/mol. It is a white to yellow crystalline powder.
This compound is commonly used in borane reactions in organic synthesis, and it is a common type of boric acid reagents. It can react with aromatic aldehydes, ketones and other substrates to form borate compounds. These boronic esters can further participate in reactions such as Suzuki-Miyaura coupling reactions and stereoselective reduction reactions, thereby synthesizing various organic compounds.
The method for preparing (2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid can generally be achieved by chemical synthesis. A general method of preparation is the reaction of 2-methyl-4-chloroaniline with dimethyl carbonate in dimethylformamide to give 2-methyl -4-(morpholinosulfonyl)-aniline. Subsequently, this compound is reacted with triphenylborohydrofluoride to produce the target product.
Regarding safety information,(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid is a chemical substance and should be handled with care. For chemical laboratories or professionals, it is recommended to operate under well-ventilated conditions and take appropriate personal protective measures, such as wearing gloves and glasses. During storage and disposal, it should be handled in accordance with relevant regulations. If you accidentally come into contact with the substance, flush with plenty of water and seek medical help. When handling any chemical, it is very important to ensure that the correct safe operating procedures are followed.
This compound is commonly used in borane reactions in organic synthesis, and it is a common type of boric acid reagents. It can react with aromatic aldehydes, ketones and other substrates to form borate compounds. These boronic esters can further participate in reactions such as Suzuki-Miyaura coupling reactions and stereoselective reduction reactions, thereby synthesizing various organic compounds.
The method for preparing (2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid can generally be achieved by chemical synthesis. A general method of preparation is the reaction of 2-methyl-4-chloroaniline with dimethyl carbonate in dimethylformamide to give 2-methyl -4-(morpholinosulfonyl)-aniline. Subsequently, this compound is reacted with triphenylborohydrofluoride to produce the target product.
Regarding safety information,(2-Methyl-4-(morpholinosulfonyl)-phenyl)boronic acid is a chemical substance and should be handled with care. For chemical laboratories or professionals, it is recommended to operate under well-ventilated conditions and take appropriate personal protective measures, such as wearing gloves and glasses. During storage and disposal, it should be handled in accordance with relevant regulations. If you accidentally come into contact with the substance, flush with plenty of water and seek medical help. When handling any chemical, it is very important to ensure that the correct safe operating procedures are followed.
Last Update：2024-04-10 22:29:15
