(2E)-3-(3,5-dimethoxyphenyl)prop-2-enoic acid

(2E)-3-(3,5-dimethoxyphenyl)prop-2-enoic acid - Names and Identifiers

Name	3,5-Dimethoxycinnamic acid
Synonyms	3,5-DIMETHOXYCINNAMI 5-DiMethoxycinnaMic acid predominantlytrans isomer 3,5-Dimethoxycinnamic acid 3-(3,5-Dimethoxyphenyl)propenoic acid (E)-3-(3,5-dimethoxyphenyl)acrylic acid (E)-3-(3,5-diMethoxyphenyl)acrylic acid 3-(3,5-dimethoxyphenyl)prop-2-enoic acid (2E)-3-(3,5-dimethoxyphenyl)prop-2-enoate (2E)-3-(3,5-dimethoxyphenyl)prop-2-enoic acid 3,5-dimethoxycinnamic acid, predominantly trans 3-(3,5-Dimethoxyphenyl)prop-2-enoic acid, 3-(3,5-Dimethoxyphenyl)acrylic acid
CAS	16909-11-8
EINECS	240-956-8
InChI	InChI=1/C11H12O4/c1-14-9-5-8(3-4-11(12)13)6-10(7-9)15-2/h3-7H,1-2H3,(H,12,13)/p-1/b4-3+

(2E)-3-(3,5-dimethoxyphenyl)prop-2-enoic acid - Physico-chemical Properties

Molecular Formula	C11H12O4
Molar Mass	208.21
Density	1.0627 (rough estimate)
Melting Point	174-175°C(lit.)
Boling Point	267.4°C (rough estimate)
Flash Point	148.5°C
Water Solubility	31.44mg/L(25 ºC)
Vapor Presure	2.33E-06mmHg at 25°C
Appearance	Solid
pKa	4.33±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.4389 (estimate)
MDL	MFCD00004389

(2E)-3-(3,5-dimethoxyphenyl)prop-2-enoic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29163990

(2E)-3-(3,5-dimethoxyphenyl)prop-2-enoic acid - Introduction

3,5-dimethoxycinnamic acid is an organic compound with the chemical formula C11H12O4. It is a derivative of cinnamic acid and has the following properties:

1. Appearance: 3,5-dimethoxycinnamic acid is a white crystalline solid.
2. Solubility: it can be dissolved in organic solvents such as ethanol, acetone and dichloromethane, slightly soluble in water.
3. Melting Point: its melting point is 160-165 ℃.
4. Stability: 3,5-dimethoxycinnamic acid is relatively stable at room temperature.

The main uses of 3,5-dimethoxycinnamic acid include the following:

1. Cosmetics: It is widely used in skin care products and makeup, as a fragrance and preservative.
2. Drug: Because of its antioxidant and anti-inflammatory effects, it is studied in the field of medicine for the treatment of inflammation-related diseases.
3. Food additives: it can be used as food preservatives and antioxidants.

The preparation of 3,5-dimethoxycinnamic acid can be achieved by the methyl esterification reaction of cinnamic acid. The specific preparation method may vary, but a common method is to esterify cinnamic acid with methanol under the action of a catalyst to generate 3,5-dimethoxycinnamic acid methyl ester, the methyl ester is then hydrolyzed to give 3,5-dimethoxycinnamic acid.

When using or handling 3,5-dimethoxycinnamic acid, you need to pay attention to the following safety information:

1. Pay attention to avoid inhaling its dust or generating its solution vapor.
2. Avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
3. Be sure to use it in a well-ventilated place and wear appropriate personal protective equipment, such as safety glasses and gloves.
4. Store 3,5-dimethoxycinnamic acid in a dry, cool place, away from fire and oxidant.
5. Follow the relevant safety procedures and disposal requirements to prevent harm to humans and the environment.

Please note that the above information is for reference only. For specific operation and application, please consult a professional or refer to relevant reliable literature.

Last Update：2024-04-09 21:21:28