(2E)-N-(2-Bromophenyl)-3-phenylacrylamide

(2E)-N-(2-Bromophenyl)-3-phenylacrylamide - Names and Identifiers

Name	N-(2-bromophenyl)cinnamamide
Synonyms	N-(2-bromophenyl)cinnamamide N-(2-bromophenyl)-3-phenyl-2-propenamide N-(2-BROMOPHENYL)-3-PHENYLPROP-2-ENAMIDE (2E)-N-(2-Bromophenyl)-3-phenylacrylamide (2E)-N-(2-bromophenyl)-3-phenylprop-2-enamide 2-propenamide, N-(2-bromophenyl)-3-phenyl-, (2E)-
CAS	71910-51-5
InChI	InChI=1/C15H12BrNO/c16-13-8-4-5-9-14(13)17-15(18)11-10-12-6-2-1-3-7-12/h1-11H,(H,17,18)/b11-10+

(2E)-N-(2-Bromophenyl)-3-phenylacrylamide - Physico-chemical Properties

Molecular Formula	C15H12BrNO
Molar Mass	302.17
Density	1.455g/cm³
Boling Point	470.4°C at 760 mmHg
Flash Point	238.3°C
Vapor Presure	5.09E-09mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.686

(2E)-N-(2-Bromophenyl)-3-phenylacrylamide - Introduction

N-(2-bromophenyl)cinnamamide is an organic compound whose chemical structural formula is C16H12BrNO. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: N-(2-bromophenyl) is cinnamamide in the form of a white solid.
-Solubility: It is soluble in common organic solvents (such as ethanol, dimethylformamide).
-Melting point: The melting point of N-(2-bromophenyl)cinnamamide is about 110-114 degrees Celsius.

Use:
-Chemical synthesis: N-(2-bromophenyl)cinnamamide has important applications in drug synthesis and organic chemistry. It can be used as an intermediate in the synthesis of biologically active target compounds, for example for the preparation of lactam drugs.
-Component analysis: N-(2-bromophenyl)cinnamamide can be used as a standard and reference substance in liquid chromatography.

Preparation Method:
The preparation of N-(2-bromophenyl)cinnamamide can be completed by the following steps:
1.2-Bromoaniline reacts with cinnamoyl chloride to generate N-(2-bromophenyl)cinnamamide. The reaction process may be carried out in an organic solvent such as ethanol or dimethylformamide.
2. The final product was purified by crystallization, filtration and washing.

Safety Information:
- N-(2-bromophenyl)cinnamamide are generally stable and safe under normal conditions of use.
-Like other organic compounds, it may be irritating to the skin, eyes and respiratory tract, so appropriate safety measures should be taken when handling, such as wearing protective gloves and goggles.
-When storing, keep it in a cool, dry place and away from fire and flammable substances.
-Seek medical advice if large amounts of N-(2-bromophenyl)cinnamamide are ingested or come into contact with them.

Last Update：2024-04-09 20:49:11