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(2R)-2-Hydroxyisovaleric acid

D-ALPHA-HYDROXYISOVALERIC ACID

CAS: 17407-56-6

Molecular Formula: C5H10O3

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(2R)-2-Hydroxyisovaleric acid - Names and Identifiers

Name D-ALPHA-HYDROXYISOVALERIC ACID
Synonyms D-Valic acid
D-a-Hydroxyisovaleric acid
d-α-hydroxyisovaleric acid
(2R)-2-Hydroxyisovaleric acid
D-ALPHA-HYDROXYISOVALERIC ACID
D-ALPHA-HYDROXYSOVALERIC ACID)
(2R)-2-Hydroxy-3-methylbutyric acid
(R)-2-Hydroxy-3-methylbutanoic acid
(2R)-2-HYDROXY-3-METHYLBUTANOIC ACID
CAS 17407-56-6

(2R)-2-Hydroxyisovaleric acid - Physico-chemical Properties

Molecular FormulaC5H10O3
Molar Mass118.13
Density1.136±0.06 g/cm3(Predicted)
Melting Point64-67°C
Boling Point237.6±13.0 °C(Predicted)
BRN1721139
pKa3.87±0.16(Predicted)
Storage ConditionInert atmosphere,2-8°C

(2R)-2-Hydroxyisovaleric acid - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
WGK Germany3
FLUKA BRAND F CODES3-10

(2R)-2-Hydroxyisovaleric acid - Introduction

D-ALPHA-HYDROXYISOVALERIC ACID, also known as D-α-hydroxyisovaleric acid (D-ALPHA-HYDROXYISOVALERIC ACID), is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
D-ALPHA-HYDROXYISOVALERIC ACID is a colorless crystalline solid. It is sparingly soluble in water, but soluble in polar organic solvents such as alcohols and ethers. It has a melting point of about 123-125°C. The chemical properties of this compound are mainly reflected in its acidity, which can react with bases to form the corresponding salts.

Use:
D-ALPHA-HYDROXYISOVALERIC ACID is widely used in organic synthesis and is often used as a raw material for the synthesis of chiral drugs. It can also be used as a reference for chiral recognition analysis for the development and validation of analytical methods.

Preparation Method:
The preparation method of D-ALPHA-HYDROXYISOVALERIC ACID is more complicated, and it is generally obtained by chiral chemical reaction of symmetrical substances. A common preparation method is to use chiral catalysts to catalyze the asymmetric hydration reaction of ethylene cyclopentene alcohol to obtain the product D-ALPHA-HYDROXYISOVALERIC ACID.

Safety Information:
D-ALPHA-HYDROXYISOVALERIC ACID currently has no reported characteristics that present a significant security risk. However, as a chemical, appropriate safety measures must be taken. Avoid contact with skin and eyes, avoid inhalation or ingestion. Wear appropriate personal protective equipment such as chemical protective gloves and goggles during use.

Please note that information from other reliable sources may be required depending on the circumstances and requirements of use.
Last Update:2024-04-09 20:45:29
(2R)-2-Hydroxyisovaleric acid
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(2R)-2-Hydroxyisovaleric acid
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