(2R)-pyrrolidin-2-ylmethanamine dihydrochloride
(2R)-pyrrolidin-2-ylmethanamine dihydrochloride
CAS: 119020-04-1
Molecular Formula: C5H12N2.2ClH
(2R)-pyrrolidin-2-ylmethanamine dihydrochloride - Names and Identifiers
(2R)-pyrrolidin-2-ylmethanamine dihydrochloride - Physico-chemical Properties
| Molecular Formula | C5H12N2.2ClH |
| Molar Mass | 173.086 |
| Melting Point | 124-130℃ |
| Appearance | Solid |
| Color | White to yellow to brown |
| Storage Condition | -20°C |
| Sensitive | Moisture Sensitive |
(2R)-pyrrolidin-2-ylmethanamine dihydrochloride - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 2 |
| HS Code | 29339900 |
(2R)-pyrrolidin-2-ylmethanamine dihydrochloride - Introduction
R-2-Aminomethylpyrrolidine dihydrochloride (R-2-amino-pyrrolidine dihydrochloride) is an organic compound with the following properties:
1. appearance: usually white solid or crystalline powder.
2. Solubility: Soluble in water, soluble in ethanol, chloroform and ether.
3. Melting point: about 270-280°C.
The main uses of R-2-aminomethylpyrrolidine dihydrochloride include:
1. pharmaceutical field: commonly used as intermediates or reducing agents for the synthesis of various drugs.
2. organic synthesis: can be used to synthesize compounds with biological activity.
3. chemical research: used for catalytic reaction or as a ligand to participate in the coordination of metal ions.
The preparation of the compound generally includes the following steps:
1. Dissolve pyrrolidine in acidic solution.
2. Add the appropriate amount of amine to the solution.
3. Reaction at low temperature for several hours to form R-2-aminomethylpyrrolidine.
4. The reaction product is filtered or crystallized to obtain a solid product.
5. Salinization using hydrochloric acid solution to produce R-2-aminomethylpyrrolidine dihydrochloride.
Regarding its safety information, R-2-aminomethylpyrrolidine dihydrochloride is a low-toxic compound. But still need to pay attention to the following safety measures:
1. Avoid direct contact with skin, eyes and mucous membranes. If contact occurs, rinse immediately with plenty of water.
2. in the operation should wear appropriate protective gloves and glasses, to ensure good ventilation conditions.
3. should be stored in a dry, cool, ventilated place, away from fire and flammable materials.
4. Avoid inhaling its dust, so it is recommended to wear respiratory protection when using it.
5. operation, should comply with the relevant laboratory safety procedures and personal protective equipment use regulations.
Reference should be made to reliable laboratory manuals or safety data forms provided by the manufacturer, depending on the situation and needs.
1. appearance: usually white solid or crystalline powder.
2. Solubility: Soluble in water, soluble in ethanol, chloroform and ether.
3. Melting point: about 270-280°C.
The main uses of R-2-aminomethylpyrrolidine dihydrochloride include:
1. pharmaceutical field: commonly used as intermediates or reducing agents for the synthesis of various drugs.
2. organic synthesis: can be used to synthesize compounds with biological activity.
3. chemical research: used for catalytic reaction or as a ligand to participate in the coordination of metal ions.
The preparation of the compound generally includes the following steps:
1. Dissolve pyrrolidine in acidic solution.
2. Add the appropriate amount of amine to the solution.
3. Reaction at low temperature for several hours to form R-2-aminomethylpyrrolidine.
4. The reaction product is filtered or crystallized to obtain a solid product.
5. Salinization using hydrochloric acid solution to produce R-2-aminomethylpyrrolidine dihydrochloride.
Regarding its safety information, R-2-aminomethylpyrrolidine dihydrochloride is a low-toxic compound. But still need to pay attention to the following safety measures:
1. Avoid direct contact with skin, eyes and mucous membranes. If contact occurs, rinse immediately with plenty of water.
2. in the operation should wear appropriate protective gloves and glasses, to ensure good ventilation conditions.
3. should be stored in a dry, cool, ventilated place, away from fire and flammable materials.
4. Avoid inhaling its dust, so it is recommended to wear respiratory protection when using it.
5. operation, should comply with the relevant laboratory safety procedures and personal protective equipment use regulations.
Reference should be made to reliable laboratory manuals or safety data forms provided by the manufacturer, depending on the situation and needs.
Last Update：2024-04-09 21:54:55
