(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite
2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS: 330628-04-1
Molecular Formula: C43H53N8O7P
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite - Names and Identifiers
| Name | 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite |
| Synonyms | DMT-dG(dmf) amidite DMF-dG Phosphoramidite DMF-dG-CE Phosphoramidite 2'-Deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite N2-(dimethylamino)methylene-deoxyguanosine Phosphoramidite N4-(Dimethylamino) methylene)-5'-O-(dimethoxytrityl)-2'-deoxyguanosine-3'-N,N-diisopropyl(cyanoethyl) phosphoramidite N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-(((E)-(DIMETHYLAMINO)METHYLENE)AMINO)-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE |
| CAS | 330628-04-1 |
| EINECS | 2017-001-1 |
| InChIKey | YRQAXTCBMPFGAN-UNHDIWNRSA-N |
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite - Physico-chemical Properties
| Molecular Formula | C43H53N8O7P |
| Molar Mass | 824.9 |
| Boling Point | 876.3±75.0 °C(Predicted) |
| Appearance | powder |
| Color | white to off-white |
| pKa | 3.80±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29349990 |
(2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((E)-(dimethylamino)methyleneamino)-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3-yl 2-cyanoethyl diisopropylphosphoramidite - Introduction
2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite is a deoxyguanosine phosphoramidite monomer rich in dimethylformamide groups and dimethylformamide groups. Its properties include high chemical stability, good solubility, easy synthesis and purification.
2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite is mainly used in nucleic acid chemical synthesis, such as synthetic oligonucleotides and oligonucleotide modification. It can combine with other nucleotide monomers to form guanosine chains through phosphodiester bonds, thereby constructing DNA or RNA sequences. The introduction of the monomer can increase the functionality of the nucleic acid sequence, change its hydrophilicity, stability, hybridization characteristics, etc.
2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite is usually prepared by organic synthesis methods. First, a dimethylformamide group is synthesized by reacting a protecting group and a ligand. The dimethylformamide group is then subjected to an activation reaction with the guanosine backbone to form a phosphoramidite monomer. Finally, 2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite with high purity was obtained by purification and structural characterization.
When using 2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite, you need to pay attention to its safety. It may be toxic to the human body, should avoid inhalation, contact with the skin and ingestion. Wear suitable personal protective equipment such as gloves, protective glasses and laboratory coats during use. In addition, it should be operated under well-ventilated laboratory conditions to avoid harmful gases or vapors. When disposing of waste, the relevant environmental and hazardous waste disposal regulations should be followed.
2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite is mainly used in nucleic acid chemical synthesis, such as synthetic oligonucleotides and oligonucleotide modification. It can combine with other nucleotide monomers to form guanosine chains through phosphodiester bonds, thereby constructing DNA or RNA sequences. The introduction of the monomer can increase the functionality of the nucleic acid sequence, change its hydrophilicity, stability, hybridization characteristics, etc.
2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite is usually prepared by organic synthesis methods. First, a dimethylformamide group is synthesized by reacting a protecting group and a ligand. The dimethylformamide group is then subjected to an activation reaction with the guanosine backbone to form a phosphoramidite monomer. Finally, 2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite with high purity was obtained by purification and structural characterization.
When using 2 '-Deoxy-N2-DMF-5'-O-DMT-guanosine 3 '-CE phosphoramidite, you need to pay attention to its safety. It may be toxic to the human body, should avoid inhalation, contact with the skin and ingestion. Wear suitable personal protective equipment such as gloves, protective glasses and laboratory coats during use. In addition, it should be operated under well-ventilated laboratory conditions to avoid harmful gases or vapors. When disposing of waste, the relevant environmental and hazardous waste disposal regulations should be followed.
Last Update：2024-04-09 21:01:54
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Product Name: N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE Visit Supplier Webpage Request for quotationCAS: 330628-04-1
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Product Name: 5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite Request for quotationCAS: 330628-04-1
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Product Name: N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE Visit Supplier Webpage Request for quotationCAS: 330628-04-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: 5'-O-DMT-N2-DMF-2'-deoxyguanosine 3'-CE phosphoramidite Request for quotationCAS: 330628-04-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
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