(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester - Names and Identifiers
Name | N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester
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Synonyms | Boc-Cis-D-Hyp-OMe Methyl cis-Boc-4-hydroxy-D-prolinate Methy cis-1-Boc-4-hydroxy-D-prolinate METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE Boc-cis-4-hydroxy-D-proline methyl ester N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester (2R,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (2R,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate 1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate (2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-
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CAS | 114676-69-6
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EINECS | 675-952-9 |
InChI | InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8-/m1/s1 |
(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester - Physico-chemical Properties
Molecular Formula | C11H19NO5
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Molar Mass | 245.27 |
Density | 1.216±0.06 g/cm3(Predicted) |
Melting Point | 76 °C |
Boling Point | 335.2±42.0 °C(Predicted) |
Flash Point | 156.6°C |
Vapor Presure | 8.47E-06mmHg at 25°C |
Appearance | Powder |
Color | White |
pKa | 14.27±0.40(Predicted) |
Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Refractive Index | 1.5 |
MDL | MFCD00797548 |
(2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester - Introduction
Cis-1-BOC-4-hydroxy-D-proline methyl ester is an organic compound with the following properties:
1. appearance: usually white or white crystalline powder.
2. Solubility: Soluble in common organic solvents such as methanol, ethanol and dimethylformamide.
3. stability: relatively stable at room temperature, but heat, light and acidic conditions may cause decomposition reaction.
The main uses of cis-1-BOC-4-hydroxy-D-proline methyl ester are as follows:
1. chemical synthesis: can be used as an intermediate in organic synthesis, for the synthesis of other compounds, such as drugs, dyes, etc.
2. Peptide synthesis: It can be used as an important raw material for the synthesis of peptides or proteins of specific sequences.
preparation method: there are many preparation methods of cis-1-BOC-4-hydroxy-D-proline methyl ester. a common synthesis method is to react 4-hydroxy-D-proline with a methyl esterification agent (such as methanol and methyl carbonic acid), and carry out esterification reaction under alkaline conditions to obtain the target product.
Safety Information: Methyl cis-1-BOC-4-hydroxy-D-proline is dangerous and may cause irritation to the skin, eyes and respiratory tract. During the operation, you should wear appropriate protective equipment to avoid direct contact with skin, eyes or inhalation of dust. At the same time, pay attention to the safe operation during storage and handling, and ensure that it is far away from the fire source and oxidant. If necessary, it is necessary to follow the relevant safety operation procedures or consult a professional.
Last Update:2024-04-09 21:11:58