(2RS)-2-(2-Oxopyrrolidin-1-yl)butanoic acid
Ethyl-2-oxo-1-pyrrolidine acetic acid
CAS: 67118-31-4;61516-73-2
Molecular Formula: C8H13NO3
(2RS)-2-(2-Oxopyrrolidin-1-yl)butanoic acid - Names and Identifiers
| Name | Ethyl-2-oxo-1-pyrrolidine acetic acid |
| Synonyms | Levetiracetam EP Impurity A ETHYL 2-OXO-1-PYRROLIDINEACETATE 2-(2-oxopyrrolidin-1-yl)butanamide Ethyl (2-oxopyrrolidin-1-yl)acetate Ethyl-2-oxo-1-pyrrolidineacetic acid Ethyl-2-oxo-1-pyrrolidine acetic acid ethyl 2-(2-oxopyrrolidin-1-yl)acetate 2-(2-oxopyrrolidin-1-yl)butanoic acid alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid (2RS)-2-(2-Oxopyrrolidin-1-yl)butanoic acid 2-(2-oxo-1-pyrrolidinyl)acetic acid ethyl ester |
| CAS | 67118-31-4 61516-73-2 |
| EINECS | 1308068-626-2 |
| InChI | InChI=1/C8H13NO3/c1-2-6(8(11)12)9-5-3-4-7(9)10/h6H,2-5H2,1H3,(H,11,12) |
| InChIKey | IODGAONBTQRGGG-UHFFFAOYSA-N |
(2RS)-2-(2-Oxopyrrolidin-1-yl)butanoic acid - Physico-chemical Properties
| Molecular Formula | C8H13NO3 |
| Molar Mass | 171.19 |
| Density | 1.227 |
| Melting Point | 155-158 °C |
| Boling Point | 371.0±25.0 °C(Predicted) |
| Flash Point | 178.16°C |
| Solubility | Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | neat |
| Color | White to Off-White |
| pKa | 3.76±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.517 |
(2RS)-2-(2-Oxopyrrolidin-1-yl)butanoic acid - Introduction
Ethyl-2-oxo-1-pyrrolidine acid, also known as acetylpyrrole and pyrrolidone acetate, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: A colorless or yellowish solid
-Molecular formula: C8H13NO3
-Molecular weight: 171.19g/mol
-Melting point: 96-98°C
-Boiling Point: 315-317°C
-Solubility: insoluble in water, dissolved in ethanol, ether and other organic solvents
Use:
-Pharmaceutical field: Pyrrolidone acetate is a synthetic intermediate that can be used to synthesize some drugs, such as cephalosporins, sulfonamides and narcotic drugs.
-Auxiliary field: Pyrrolidone acetate can be used as a ligand for some catalysts and participate in organic synthesis reactions.
Preparation Method:
Pyrrolidone acetate is generally synthesized by the following steps:
1. Condensation reaction of 2-pyrrole formaldehyde and acetic acid in an equimolar ratio of substrates to obtain 2-ethoxycarbonyl pyrrole.
2. Oxidation of 2-ethoxycarbonyl pyrrole to obtain Ethyl-2-oxo-1-pyrrolidine acid.
Safety Information:
Nature:
-Appearance: A colorless or yellowish solid
-Molecular formula: C8H13NO3
-Molecular weight: 171.19g/mol
-Melting point: 96-98°C
-Boiling Point: 315-317°C
-Solubility: insoluble in water, dissolved in ethanol, ether and other organic solvents
Use:
-Pharmaceutical field: Pyrrolidone acetate is a synthetic intermediate that can be used to synthesize some drugs, such as cephalosporins, sulfonamides and narcotic drugs.
-Auxiliary field: Pyrrolidone acetate can be used as a ligand for some catalysts and participate in organic synthesis reactions.
Preparation Method:
Pyrrolidone acetate is generally synthesized by the following steps:
1. Condensation reaction of 2-pyrrole formaldehyde and acetic acid in an equimolar ratio of substrates to obtain 2-ethoxycarbonyl pyrrole.
2. Oxidation of 2-ethoxycarbonyl pyrrole to obtain Ethyl-2-oxo-1-pyrrolidine acid.
Safety Information:
Last Update：2024-04-09 02:00:47
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Multiple SpecificationsSpot supply
Product Name: Levetiracetam Impurity 8（Levetiracetam EP Impurity A） Visit Supplier Webpage Request for quotationCAS: 67118-31-4
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: Etiracetam Carboxylic Acid Visit Supplier Webpage Request for quotationCAS: 67118-31-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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