(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid

(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid - Names and Identifiers

Name	(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid
Synonyms	3-Hydroxy-L-Leucine L-THREO-HYDROXYLEUCINE L-Threo-Hydroxyleucine (2S,3R)-3-Hydroxyleucine L(+)-THREO-3-HYDROXYLEUCINE L(+)-Threo-3-Hydroxyleucine (2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid (2S,3R)-(+)-2-Amino-3-Hydroxy-4-Methylpentanoic Acid (2S,3R)-(+)-2-Amino-3-hydroxy-4-methyl-pentanoicacid(e.e.) 2-amino-3-hydroxy-4-methylpentanoic acid (non-preferred name) (2S,3S)-2-ammonio-3-hydroxy-4-methylpentanoate (non-preferred name) (2S,3R)-2-ammonio-3-hydroxy-4-methylpentanoate (non-preferred name)
CAS	10148-71-7
InChI	InChI=1/C6H13NO3/c1-3(2)5(8)4(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t4-,5+/m0/s1

(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid - Physico-chemical Properties

Molecular Formula	C6H13NO3
Molar Mass	147.17
Density	1.2006 (rough estimate)
Melting Point	225-227 °C
Boling Point	267.28°C (rough estimate)
Specific Rotation(α)	18.5 º (c=1, 6N HCl 25 ºC)
Flash Point	146.7°C
Vapor Presure	2.87E-05mmHg at 25°C
pKa	2.40±0.25(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.4240 (estimate)

(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid - Risk and Safety

Safety Description	S24/25 - Avoid contact with skin and eyes. Solubility -
HS Code	29224985

(2S,3R)-(+)-2-Amino-3-hydroxy-4-methylpentanoic acid - Introduction

(2S,3R)-(+)-2-amino-3-hydroxy-4-methylpentanoic acid is a chiral molecule, also known as 2-amino-3-hydroxy-4-methylpentanoic acid. The following is a description of its nature, use, formulation and safety information:

Nature:
(2S,3R)-( )-2-amino-3-hydroxy-4-methylpentanoic acid is a solid with a white to off-white appearance. Its chemical formula is C6H13NO3 and its molecular weight is 147.17g/mol.

Use:
(2S,3R)-( )-2-amino-3-hydroxy-4-methylpentanoic acid is a chiral amino acid that can be used to synthesize drugs and other organic compounds. It is used in the pharmaceutical field as an intermediate for the synthesis of anti-viral, anti-cancer and anti-biologically active compounds. In addition, it can also be used in the synthesis of chiral ligands and catalysts.

Preparation Method:
(2S,3R)-( )-2-amino-3-hydroxy-4-methylpentanoic acid is usually prepared by chemical synthesis. The specific preparative steps relate to the reaction conditions and reagents used, and these details are beyond the scope of this introduction.

Safety Information:
(2S,3R)-( )-2-amino-3-hydroxy-4-methylpentanoic acid has limited safety information, so it needs to be handled with caution when using it. It may cause irritation to the eyes, skin and respiratory tract. Wear appropriate personal protective equipment, including goggles, gloves, and respiratory protection equipment during operation. In addition, avoid exposing it to fire sources or high temperature environments to prevent explosions or fires. When using and storing, please strictly follow the safety procedures of chemicals.

Last Update：2024-04-09 20:52:54