(3-Methoxy-phenyl)-carbamic acid tert-butyl ester

(3-Methoxy-phenyl)-carbamic acid tert-butyl ester - Names and Identifiers

Name	tert-butyl 3-methoxyphenylcarbamate
Synonyms	N-Boc-m-anisidine N-Boc-3-Methoxyaniline tert-Butyl (3-methoxyphenyl) 1-(Boc-amino)-3-methoxybenzene tert-butyl 3-methoxyphenylcarbamate (3-Methoxy-phenyl)-carbamic acid tert-butyl ester Carbamic acid, N-(3-methoxyphenyl)-, 1,1-dimethylethyl ester
CAS	60144-52-7

(3-Methoxy-phenyl)-carbamic acid tert-butyl ester - Physico-chemical Properties

Molecular Formula	C12H17NO3
Molar Mass	223.27
Melting Point	55-60°C
Flash Point	>110℃
Storage Condition	2-8℃

(3-Methoxy-phenyl)-carbamic acid tert-butyl ester - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R36 - Irritating to the eyes R52 - Harmful to aquatic organisms
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3

(3-Methoxy-phenyl)-carbamic acid tert-butyl ester - Upstream Downstream Industry

Downstream Products

4-Methoxy-indoline-2,3-dione

(3-Methoxy-phenyl)-carbamic acid tert-butyl ester - Introduction

tert-butyl 3-methoxyphenylcarbamate is a compound whose chemical name is tert-butyl 3-methoxyphenylcarbamate. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
tert-butyl 3-methoxyphenylcarbamate is a white to pale yellow solid that is soluble in organic solvents such as dimethylformamide (DMF), acetonitrile, and dichloromethane. It has a lower melting point and boiling point, better stability.

Use:
tert-butyl 3-methoxyphenylcarbamate can be used as an intermediate in organic synthesis. It is commonly used in the introduction and removal of protecting groups in multi-step synthesis, by protecting or deprotecting the amino group in the target molecule. In addition, it can also be used as an important raw material in drug synthesis and material science.

Method:
The synthesis of tert-butyl 3-methoxyphenylcarbamate is usually carried out by reacting N-BOC-aniline and 3-methoxybenzoic acid (3-methoxybenzoic acid) under appropriate solvent and temperature conditions.

Safety Information:
tert-butyl 3-methoxyphenylcarbamate is a chemical and must be operated under appropriate laboratory conditions. Relevant safety practices such as wearing appropriate personal protective equipment (e. G. Gloves and goggles) and avoiding contact with skin and eyes should be observed. In addition, it should be stored in a dry, cool, well-ventilated place, and stored separately from oxidants and strong acids to avoid fire and high temperatures. For detailed safety information, refer to the chemical safety data sheet (SDS) or consult relevant professionals.

Last Update：2024-04-09 20:52:54